β-Glucuronidase at the gut-liver interface: Structural selectivity, enterohepatic reactivation, and the pharmacomicrobiomic case for precision inhibition.
β-Glucuronidase (β-G, EC 3.2.1.31) reverses phase II glucuronidation, and microbial β-G at the gut-liver interface reactivates biliary and circulating conjugates, closing enterohepatic loops for drugs, estrogens, bile acids, and bilirubin. …
GREB1 as a Context-Dependent Molecular Switch in Endometrial Estrogen-Progesterone Crosstalk: From Physiological Receptivity to Endometriosis Pathogenesis-A Narrative Review.
In this narrative review, we summarize current evidence regarding the endometrium undergoes cyclic remodeling driven by estrogen (E2) and progesterone (P4) signaling, with precise coordination essential for receptivity and pregnancy …
Colorectal Carcinoma Metastatic to the Breast Mimicking Inflammatory Breast Cancer With Mismatch Repair Status Discordant From a Prior Endometrial Primary: A Case Report and a Review of the Literature - Cureus
Colorectal Carcinoma Metastatic to the Breast Mimicking Inflammatory Breast Cancer With Mismatch Repair Status Discordant From a Prior Endometrial Primary: A Case Report and a Review of the Literature Cureus