Latest Articles

Endocrine roles of vitamin D in female reproduction: Mechanisms and clinical implications.

Vitamin D a fat-soluble steroid hormone signals through Vitamin D Receptors (VDRs) located throughout the ovaries, uterus, placenta, hypothalamus, and pituitary gland, influencing immune regulation and female reproductive physiology. This …

Endometrial HOXA-10, HOXA-11, ß-1 integrin, ECM-1, FAK, and CD44 immunohistochemical expressions in endometriosis-related recurrent IVF failure: a retrospective case-control study.

Intra-Patient Variability in the Number of Retrieved Oocytes and Ovarian Response Categories Between Consecutive IVF Cycles.

To examine intra-patient variability in retrieved oocyte numbers across consecutive in-vitro fertilization (IVF) ovarian stimulation (OS) cycles with an identical OS protocol.

Endometriosis-Related Impairment in Assisted Reproductive Technologies: Inflammatory Profiles, Oocyte Competence, and Embryo Development.

Background: Endometriosis is associated with infertility and impaired assisted reproductive technology (ART) outcomes, potentially due to an altered follicular microenvironment characterized by chronic inflammation. This study investigates the systemic and …

The letrozole use in reproductive medicine: Beyond aromatase inhibition - a comprehensive review.

Letrozole and other aromatase inhibitors are increasingly recognized as first-line ovulation induction (OI) medications, offering an efficient and physiologic approach to ovarian stimulation that enhances outcomes in reproductive medicine. By …

Metabolomic profiling of follicular fluid reveals unique pathways in endometriosis and infertility etiologies: a pilot study.

This study investigates metabolic profiles in follicular fluid of patients with endometriosis (EM), polycystic ovary syndrome (PCOS), tubal blockage (TB), and unexplained infertility (UEI), assessing their associations with follicular development …

Development and validation of a clinical nomogram for predicting cumulative live birth rate in ovarian endometrioma patients undergoing ethanol sclerotherapy and in vitro fertilization/intracytoplasmic sperm injection.

Effective individualized tools to predict cumulative live birth rates are lacking for patients with ovarian endometriomas undergoing In Vitro Fertilization or Intracytoplasmic Sperm Injection after ultrasound-guided ethanol sclerotherapy. This study …

Spontaneous midtrimester uterine rupture in a primigravida with endometriosis: A case report and literature review.

Spontaneous uterine rupture in an unscarred uterus is a rare but life-threatening obstetric emergency, and endometriosis has increasingly been recognized as a potential risk factor. We report a 33-year-old primigravid …

Average oocyte quality index as a method for scoring dysmorphic oocytes in women with ovarian endometrioma undergoing in vitro fertilization and its correlation with ovarian reserve.

This study investigated whether the average oocyte quality index (AOQI), used as a dysmorphic oocyte scoring system, is higher in women with ovarian endometrioma than in those with unexplained infertility …

Integrating IVF and Surgical Management in Endometriosis-Associated Infertility: A Review.

Endometriosis is a chronic, debilitating condition characterized by heterogenous clinical manifestations. It has a prevalence of 5-10% in women of reproductive age, and 30-50% of individuals with endometriosis are affected …