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SLC25A1-Mediated Cholesterol Accumulation Promotes Endometriosis Progression by Enhancing Endometrial Stromal Cell Proliferation, Invasion, and M2 Macrophage Polarization.

Endometriosis is an estrogen-dependent chronic inflammatory disorder. Cholesterol (CHO) has been reported to be closely associated with estrogen synthesis and inflammatory responses. Nevertheless, the mechanisms underlying the effects of cholesterol …

Published: Jan. 1, 2026, midnight
Role of Phytoestrogens in Endometriosis.

To investigate the therapeutic potential of phytoestrogens in the management of endometriosis and to elucidate their mechanisms of action based on current preclinical and clinical evidence.

Published: Dec. 12, 2025, midnight
Assessing the effectiveness of a pelvic pain management programme: does an endometriosis diagnosis influence outcome (a comparative analysis of outcomes in women with and without endometriosis).

Pain Management Programmes (PMPs) are recommended for chronic pain, but their effectiveness for endometriosis-associated chronic pelvic pain (CPP) remains unclear. This study evaluates outcomes from a specialised, multidisciplinary Pelvic Pain …

Published: Dec. 12, 2025, midnight
Physical activity phenotypes in endometriosis using unsupervised learning via functional mixture models.

Endometriosis is a chronic condition associated with severe pelvic pain, dysmenorrhea, infertility, and worsening quality of life. Regular physical activity (PA) is effective for pain management and reducing chronic disease …

Published: Dec. 11, 2025, midnight
The Role of Hysterectomy in the Management of Endometriosis.

Endometriosis is a complex, chronic disorder that has the potential to produce long-term negative impact on the life and function of patients who carry this diagnosis. Endometriosis is thought to …

Published: Dec. 9, 2025, midnight
Online Cognitive-Behavioral Programs for Women Living With Endometriosis: Protocol for a Scoping Review.

Endometriosis is a chronic inflammatory condition experienced by approximately 10% of women worldwide. Women living with endometriosis experience multidimensional burdens often attributed to pain, fatigue, anxiety, and depression. Treatment patterns …

Published: Dec. 8, 2025, midnight
Age-dependent variations in clinical features and operative time for endometriotic cysts.

Endometriosis with ovarian cysts is common in reproductive-age women and contributes to pain and infertility. The influence of age on clinical and surgical outcomes remains uncertain. This retrospective study analyzed …

Published: Dec. 6, 2025, midnight
Microbiota insights in endometriosis.

Endometriosis affects approximately 10% of women of reproductive age and is characterized by the presence of endometrial-like tissue outside the uterine cavity, leading to chronic pelvic pain, infertility, and a …

Published: Dec. 5, 2025, midnight
Impact of Intraoperative Clonidine on Postoperative Opioid Use in Patients With Endometriosis: A Randomized Controlled Trial.

Patients with endometriosis undergoing surgery are at risk of moderate-to-severe postoperative pain. Clonidine, an alpha-2 agonist with analgesic properties, may improve multimodal pain management in these patients.

Published: Dec. 4, 2025, midnight
Laparoscopic treatment of bilateral inguinal round ligament endometriosis.

To demonstrate the laparoscopic management of bilateral round ligament endometriosis SETTING: A tertiary referral center specializing in minimally invasive gynecologic surgery.

Published: Dec. 4, 2025, midnight
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