Identification of appropriate biomarkers is of great clinical significance for early diagnosis of endometriosis (EMs). This study aimed to comprehensively analyze the association between EMs and blood and urine biomarkers …
Endocrine disrupting chemicals (EDCs) have been associated with disorders affecting female reproductive health, although the precise causal connections and underlying pathways between these substances and such disorders remain incompletely elucidated. …
Observational studies have indicated a potential link between adenomyosis/endometriosis and adverse pregnancy outcomes (APOs), yet the potential relationship remains uncertain.
To explore the genetic associations between 91 types of blood cells (BCs) and endometriosis (EMs), providing references for the treatment of EMs. Forward Mendelian randomization (MR) analysis was conducted with …
This study aimed to investigate the causal relationship between dietary habits and nine common diseases with high female prevalence using a two-sample Mendelian randomization (MR) approach.
This mendelian randomization (MR) study aimed to investigate whether endometriosis, overall and stratified by stage (I/II vs III/IV), confers causal effects on adverse pregnancy and perinatal outcomes.
Endometriosis is a chronic inflammatory disorder with poorly understood mechanisms. Inflammatory proteins are hypothesized to play a causal role, but evidence remains limited. We performed a 2-sample Mendelian randomization study …
Although observational studies suggest a link between socioeconomic status (SES) and hormone-related gynecologic diseases, the causal direction and mediating mechanisms remain unclear. This study aims to explore the causal relationships …
While epidemiological studies have associated endometriosis with ovarian cancer risk, the causal relationships across anatomic subtypes and histotypes remain undefined. Using two-sample Mendelian randomization with 84 genetic instruments (F-statistic = …