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Human Endometriotic Lesion-Derived Small Extracellular Vesicles Impair Macrophage Function in the Peritoneal Microenvironment.

Endometriosis (EM) is a chronic inflammatory disease that affects ∼10% of women during reproductive age. It is characterised by ectopic (ECT) growth of endometrial-like tissue mainly in the pelvic cavity. …

Published: Feb. 20, 2026, midnight
Behavioral attenuation of marble burying and digging mirrors evoked and non-evoked phenotypes in the endometriosis mouse model.

Endometriosis (ENDO) is an estrogen-dependent chronic gynaecological manifestation of uterine fragments attached outside of the uterus, accompanied by debilitating chronic pelvic pain. The evoked assays often employed fail to capture …

Published: Feb. 20, 2026, midnight
Spontaneous midtrimester uterine rupture in a primigravida with endometriosis: A case report and literature review.

Spontaneous uterine rupture in an unscarred uterus is a rare but life-threatening obstetric emergency, and endometriosis has increasingly been recognized as a potential risk factor. We report a 33-year-old primigravid …

Published: Jan. 22, 2026, midnight
Copper-Targeted Therapy in Experimental Endometriosis: Effects of Ammonium Tetrathiomolybdate on Markers of the Interconnected Processes of Inflammation, Innervation, and Fibrogenesis.

Endometriosis (EDT) is a chronic, estrogen-dependent disease characterized by inflammation, fibrosis, pelvic pain, and infertility. Current therapies show limited long-term efficacy and adverse effects, underscoring the need for novel therapeutic …

Published: Jan. 22, 2026, midnight
Mucin Biology as a Local Diagnostic and Promising Therapeutic Target in Endometriosis: Expression and Glycosylation Profiling.

Endometriosis (EM) is a chronic inflammatory disease characterized by the growth of endometrial-like tissue outside the uterus, yet its molecular mechanisms remain poorly understood. This study investigated the expression of …

Published: Jan. 20, 2026, midnight
Aquaporin-9 and Endometriomas: Pathophysiological Insights from a Case-Control Study.

Endometriosis is an estrogen-dependent condition characterized by ectopic implantation of endometrial tissue, yet the molecular mechanisms underlying lesion persistence remain incompletely understood. Aquaporins (AQPs), transmembrane water channels involved in cellular …

Published: Jan. 10, 2026, midnight
The Histamine-Associated Inflammatory Landscape of Endometriosis: Molecular Profiling of HDC, HRH1-HRH4, and Cytokines Across Lesion Subtypes.

Pain in endometriosis involves not only nociceptive but also neuropathic and neurogenic components, reflecting its complex nature. Histamine, a biogenic amine, has emerged as a critical mediator connecting inflammation and …

Published: Dec. 24, 2025, midnight
Usage of methods polarization-phase mueller-matrix introscopy for early diagnosis of endometriosis based on study of dehydrated films of peritoneal fluid.

Aim: To assess the effectiveness of early diagnosis of endometriosis using polarization-phase Muller-matrix introscopy methods of scattering dehydrated films of peritoneal fluid.

Published: Dec. 18, 2025, midnight
Mesothelin as a Diagnostic Biomarker in Endometriosis: A Cross-Sectional Study.

Endometriosis is a prevalent gynecological condition often requiring invasive procedures for diagnosis. This study aimed to assess mesothelin (MSLN) as a potential non-invasive biomarker by analyzing its levels in peritoneal …

Published: Nov. 28, 2025, midnight
Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.

Endometriosis-associated ovarian carcinoma (EAOC) predominantly arises from the malignant transformation of endometriomas, yet the mechanism is incompletely defined. Spatial transcriptomic analysis of human specimens of normal endometrium, endometriomas, and EAOC …

Published: Nov. 20, 2025, midnight
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