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Fertility outcomes after conservative versus radical surgery in moderate to severe endometriosis with deep endometriosis.

Does laparoscopic radical excision of deep endometriosis (DE) and enucleation of endometrioma improve fertility outcomes and reduce recurrence rates in patients with moderate to severe endometriosis?

Published: March 13, 2026, midnight
Exploring the therapeutic potential of disulfiram in endometriosis: mechanisms targeting inflammation, oxidative stress, pyroptosis, and angiogenesis.

Endometriosis (EMS) is a prevalent, inflammatory gynecological disorder with limited effective treatments and high recurrence rates. Given the central roles of inflammation, oxidative stress, pyroptosis, and angiogenesis in its pathogenesis, …

Published: Feb. 12, 2026, midnight
2-Deoxyglucose dendrimer-enabled niclosamide delivery to FRβ-expressing macrophages alleviates endometriosis progression and associated hyperalgesia.

Endometriosis is a chronic, incurable disease. Due to limited efficacy, high recurrence rates, and serious side effects of current treatments, development of new, targeted, non-hormonal therapies is urgently needed. We …

Published: Feb. 12, 2026, midnight
Targeting HSP90 as a therapeutic approach for endometriosis: insights from proteomic analysis.

Endometriosis, a chronic inflammatory condition characterized by pain and infertility, remains a clinical challenge. Current hormonal and surgical treatments are often limited by side effects and high recurrence rates. In …

Published: Feb. 7, 2026, midnight
Therapeutic Effects of Vitamins in Endometriosis Patients: A Systematic Review of Randomized Controlled Trials.

Endometriosis is a chronic, estrogen-dependent inflammatory condition affecting approximately 10% of women of reproductive age worldwide. It is characterized by the presence of endometrial-like tissue outside the uterine cavity, which …

Published: Feb. 2, 2026, midnight
Natural products modulate programmed cell death signaling mechanism for treating endometriosis: a review.

Endometriosis (EMs) is a gynecological inflammatory disease that depends on estrogen. Its chief symptoms include dysmenorrhea, chronic pelvic pain, reduced fertility, and pelvic masses. Although various hormonal therapies and surgical …

Published: Jan. 29, 2026, midnight
Targeting endometrial stem cell in endometriosis treatment, a scoping review.

Endometriosis is characterized by the ectopic implantation of endometrial tissue affecting reproductive-aged women. Available therapies have still unmet needs namely due to recurrence rates and systemic side effects. Emerging evidence …

Published: Jan. 20, 2026, midnight
Burden analysis of uterine fibroids and endometriosis in reproductive-age women globally, in China, India, and the United States, 1990-2021.

Uterine fibroids and endometriosis are common benign gynecological diseases affecting the health of women of childbearing age, characterized by high incidence and recurrence rates. Despite the increasing global emphasis on …

Published: Jan. 13, 2026, midnight
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apoptotic form of …

Published: Dec. 19, 2025, midnight
Ethanol sclerotherapy for endometriomas: a fertility-preserving alternative.

Endometriomas are a common manifestation of endometriosis in women of reproductive age and pose a clinical challenge due to their association with pain, infertility, and compromised ovarian reserve. Surgical removal …

Published: Dec. 4, 2025, midnight
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