A multi-state survival model to identify risk factors for lethal ovarian cancer.
Given primary prevention strategies for ovarian cancer, such as surgery and medications, have inherent risks, identifying those at high risk of lethal ovarian cancer is critical. We examined pre-diagnosis factors …
Histone lactylation: a novel epigenetic bridge linking cellular metabolism to benign and malignant gynecological diseases.
Lactic acid modification of histones represents an emerging post-translational modification that establishes a critical link between cellular metabolic reprogramming and epigenetic regulation through the covalent binding of lactic acid to …