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Macrophage-derived exosomes promote proliferation, migration, and invasion of endometrial stromal cells in endometriosis and are associated with exosomal lncRNA ZFAS1: A pilot translational study.

Endometriosis (EMs) is a prevalent gynecological disorder affecting reproductive-age women. Exosomes secreted by peripheral blood macrophages may participate in EMs progression. In this pilot translational study, exosomes from peripheral blood …

Published: June 24, 2026, midnight
Revisiting endometriosis management: Polyphenols as alternative therapeutic candidates.

Endometriosis (EM) is a common gynecological disorder imposing a considerable burden on the quality of life of women through chronic pain, infertility, and other clinical manifestations. The effectiveness of management …

Published: June 24, 2026, midnight
Incidence and remission of endometriosis in Germany based on prevalence data from 35 million patients from the statutory health insurance.

Endometriosis is a chronic gynecological disease that can potentially develop as early as birth and can restrict the life of the patient. With the increasing prevalence of endometriosis in Germany, …

Published: June 23, 2026, midnight
Histone lactylation: a novel epigenetic bridge linking cellular metabolism to benign and malignant gynecological diseases.

Lactic acid modification of histones represents an emerging post-translational modification that establishes a critical link between cellular metabolic reprogramming and epigenetic regulation through the covalent binding of lactic acid to …

Published: June 23, 2026, midnight
The Clinical Impact of Patient Embarrassment in Gynecology: A Comprehensive Review of Barriers, Consequences, and Mitigation Strategies.

Patient embarrassment represents a significant yet often underrecognized barrier to effective gynecological care. This review integrates multidisciplinary evidence from Embase, PubMed, PsycINFO, and the Cochrane Library (2000-2025) to examine the …

Published: June 22, 2026, midnight
Research progress of ferroptosis in gynecological diseases.

The concept of ferroptosis debuted as a newly defined programmed cell death in 2012. Among programmed cell death mechanisms, ferroptosis stands out as being fundamentally dependent on iron. At the …

Published: June 19, 2026, midnight
ZNF143 Promotes Endometriotic Lesion Growth and Fibrosis through the Plasminogen Activator Inhibitor-1 Pathway.

Endometriosis (EMs) is a chronic, estrogen-dependent gynecological disorder characterized by the ectopic growth of endometrial tissue outside the uterus. Zinc Finger Protein 143 (ZNF143) is a DNA-binding transcription factor, yet …

Published: June 18, 2026, midnight
NK Cell Profiling: Expression of TIGIT and LAG3 as Immune Checkpoints in Advanced Endometriosis.

Endometriosis (EMS) is a gynecological condition that is associated with chronic pelvic pain and inflammation. Evidence supports the idea that natural killer (NK) cell dysfunction contributes to EMS pathogenesis; nevertheless, …

Published: June 16, 2026, midnight
Bladder Endometriosis: An Updated Narrative Review with Three Surgical Cases.

Bladder endometriosis (BE) represents a rare yet clinically significant manifestation of deep infiltrating endometriosis. It is frequently underdiagnosed owing to nonspecific urinary symptoms and the coexistence of other urological or …

Published: June 15, 2026, midnight
Burden and Trends of Six Gynecological Diseases Among Chinese Women Aged 15-49 Years, 1990-2021: Evidence from GBD 2021.

This study examines the burden of six gynecological system diseases (uterine fibroids, polycystic ovarian syndrome, endometriosis, cervical cancer, ovarian cancer, and uterine cancer) in Chinese women aged 15-49 years from …

Published: June 15, 2026, midnight
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