Endometriosis is a chronic inflammatory condition affecting 10% to 15% of reproductive-aged women. The urinary tract is the second most common extragenital site of endometriosis after the gastrointestinal tract, with …
The mechanisms by which apolipoprotein L1 (APOL1) risk variants, G1 and G2, induce kidney disease in individuals of African ancestry remain contentious.
Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptions hinder effective management, particularly …
Advances in kidney transplantation have transformed survival and quality of life for women with end-stage renal disease, necessitating a focus on long-term health care for this population. Female kidney transplant …
Herlyn-Werner-Wunderlich syndrome (OHVIRA syndrome) is a rare congenital anomaly involving the Müllerian and renal systems, classically presenting as uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. Due to its rarity …
Ureteral endometriosis (UE) is a rare but potentially devastating manifestation of deep infiltrating endometriosis, often remaining asymptomatic until irreversible renal damage occurs. We present the case of a 42-year-old woman …
Müllerian anomalies complicated by extrapelvic endometriosis are uncommon, and herniation of Müllerian remnants into the inguinal canal is exceptionally rare. These complex presentations pose significant diagnostic challenges arising from intricate …
High Mobility Group Box 1 (HMGB1) and S100 proteins are major ligands of Receptor for Advanced Glycation End-products (RAGE) and have causal roles in endometriosis lesions. Yet the AGE-RAGE pathway …
Herlyn-Werner-Wunderlich syndrome is a rare congenital anomaly characterized by uterus didelphys, obstructed hemi-vagina, and ipsilateral renal agenesis. This study aims to present a case of Herlyn-Werner-Wunderlich syndrome seen at Shifa …
Fifteen years have elapsed since the publication of the seminal work establishing the association between risk variants in the Apolipoprotein L1 (APOL1) gene and kidney disease in individuals of African …