Female reproductive disorders represent a major global health challenge. Despite their clinical heterogeneity, these conditions share core pathological mechanisms including oxidative stress, chronic inflammation, hormonal imbalance, metabolic dysfunction, extracellular matrix …
Hysterectomy is the regimen of choice for benign gynecologic diseases, including uterine myoma, adenomyosis, endometriosis, and genital prolapse. Surgeons choose hysterectomy methods based on clinical situations or patients' preferences. Even …
Arteriovenous malformations (AVMs) are vascular anomalies defined by direct communications between arteries and veins with bypassing of the capillary network. Such lesions may be congenital or acquired. In the uterus, …
Cystic adenomyoma is a rare focal cystic variant of adenomyosis, and giant lesions are particularly uncommon. Malignant transformation has been reported in endometriosis-related disease, but the molecular features of cystic …
The objective of this video is to describe a case of disseminated peritoneal leiomyomatosis (DPL) mimicking deeply infiltrating endometriosis and discuss the preoperative workup, intraoperative approach, and postoperative considerations. We …
Background: Emerging evidence suggests that lipedema may share hormonal, inflammatory, and genetic mechanisms with gynecologic diseases, particularly endometriosis. However, the extent and nature of these interrelationships remain poorly characterized, supporting …
Uterine leiomyomas or fibroids, are non-cancerous smooth muscle proliferations of the uterus, occurring mostly in women of reproductive age. Their pathogenesis involves complex growth factor interactions that regulate cellular proliferation, …
Abnormal uterine bleeding (AUB), particularly when associated with uterine leiomyomas, is a frequent cause of iron deficiency anemia among women of reproductive age. While commonly manageable, in rare instances, AUB …
Herlyn-Werner-Wunderlich syndrome is a rare congenital anomaly characterized by uterus didelphys, obstructed hemi-vagina, and ipsilateral renal agenesis. This study aims to present a case of Herlyn-Werner-Wunderlich syndrome seen at Shifa …