Latest Articles

Sex-specific mechanisms of chronic pain.

For decades, we have known that women, especially younger women, are disproportionately affected by pain disorders, including irritable bowel syndrome, endometriosis, menstrual migraines, fibromyalgia, osteoarthritis, and neuropathic pain, all of …

The Role and Mechanism of Incretins in Gynaecologic Diseases.

Obesity is a major global public health concern closely linked to the development and progression of various gynaecological disorders, particularly polycystic ovary syndrome (PCOS) and endometrial cancer. Incretins, a group …

Artificial intelligence for women's reproductive health: A scoping review of global diagnostic trends, methodological gaps, and a translational research agenda for low-resource settings.

Women's reproductive and endocrine disorders including Polycystic Ovary Syndrome (PCOS), endometriosis, thyroid disorders, infertility, and pregnancy-related complications remain a major global health burden. These conditions are especially difficult to manage …

Research progress on the role of IL‑37 in gynecological and obstetrics‑related diseases (Review).

Interleukin 37 (IL‑37), a member of the IL‑1 family, is recognized as an anti‑inflammatory cytokine. The anti‑inflammatory properties of recombinant human (rh)IL‑37 have been confirmed in vitro and its protective …

Ovarian fibrosis as a common mechanism of infertility.

Female fertility has long been explained through observation of the ovarian follicle: the number of residing follicles and the quality of the oocyte. This review argues that the tissue surrounding …

Thoracic and Umbilical Endometriosis Concurrently Presenting During Secondary Subfertility Evaluation.

Thoracic endometriosis is a rare manifestation of extra pelvic endometriosis and it is often missed because of its variable clinical presentation. A 33-year-old woman undergoing evaluation for secondary subfertility presented …

The hidden burden: connective tissue, mast cell, and autoimmune comorbidities cluster in POTS with endometriosis.

Experiences of Exercise Advice Among Women With Polyendocrine Metabolic Ovarian Syndrome and Endometriosis in Australia: A Cross-Sectional Study.

Polyendocrine metabolic ovarian syndrome (PMOS) and endometriosis are common gynecological conditions with no cure. Management is aimed at symptom relief with clinical guidelines recommending lifestyle changes including exercise. The aim …

CHRONIC OVERLAPPING PAIN CONDITIONS IN REFRACTORY UROLOGIC CHRONIC PELVIC PAIN SYNDROME (UCPPS):COMORBIDITY PATTERNS, ILLNESS BURDEN, AND TREATMENT IMPLICATIONS.

To examine Chronic Overlapping Pain Conditions (COPC) prevalence in Urologic Chronic Pelvic Pain Syndrome (UCPPS) patients and assess the independent contributions of specific COPCs and pairwise COPC combinations to severity …

Estrogens hypersensitivity syndrome in endometriosis.

Objectives. The aim of the study was to develop a diagnostic method for estrogen hypersensitivity syndrome in proliferative benign diseases of the female reproductive system. Using the example of endometriosis, …