Microvascular hypoxia and inflammation in chronic pain syndromes.
In this opinion, we propose that compromised microvascular perfusion and inflammation are fundamental drivers of chronic pain syndromes, with many of these conditions sharing a common etiology involving suboptimal blood …
Personalized Estimation of Fatigue in Endometriosis Using Wrist-Worn Actigraphy Data and Hierarchical Bayesian Modeling.
Endometriosis is a common chronic condition associated with debilitating pain and fatigue. Wearable technology has the potential to improve symptom monitoring in endometriosis where symptom severity has been traditionally evaluated …
UBE2S-mediated deubiquitination of GLUT1 via USP10 regulates glucose metabolic reprogramming and immune microenvironment to promote fibrosis in endometriosis.
Endometriosis (EM) is a chronic inflammatory disorder characterized by the growth of ectopic endometrial-like tissue and fibrosis. Metabolic reprogramming, particularly enhanced glycolysis, and immune microenvironment dysregulation are key features of …