Oxidative stress has emerged as a key factor regulating female fertility, reproductive aging, and the development of various gynecologic and pregnancy-associated diseases. While physiological concentrations of reactive oxygen species play …
Three-dimensional (3D) organoid and co-culture models have emerged as transformative tools for studying human endometrial function, implantation, and placental development, overcoming key limitations of animal and two-dimensional in vitro systems. …
Endometriomsis (EMs) is a complex and chronic gynecological disease characterized by distressing symptoms. Its pathogenesis remains unknown, and there is no effective treatment. Therefore, establishing patient-derived models is crucial for …
Phthalates (PAEs), typical endocrine-disrupting chemicals (EDCs) that accumulate in the human body to induce reproductive toxicity, have epidemiological links to endometriosis (EM), but the underlying micro-mechanisms remain unclear. Ferroptosis is …
Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions such as endometriosis, which has been historically understudied despite …
Endometriosis (EM) is driven by immune dysregulation and macrophage dysfunction, yet the underlying mechanisms remain unclear. Here, metabolomic profiling revealed excessive itaconate accumulation in EM lesions, primarily due to elevated …
Ureteral endometriosis (UE) is a rare but potentially devastating manifestation of deep infiltrating endometriosis, often remaining asymptomatic until irreversible renal damage occurs. We present the case of a 42-year-old woman …
Catamenial pneumothorax (CP) is a rare cause of recurrent spontaneous pneumothorax in women of reproductive age, typically linked to endometriosis. It usually occurs 24 h before or within 72 h …
Endometriosis(EMS) symptoms, progression, and onset are all linked to the patient's immune system dysfunction. Research on immune cells and their molecular mechanisms has long been a prime focus of EMS …
To systematically review the literature on women's sexual quality of life after Transvaginal Natural Orifice Endoscopic Surgery (vNOTES) for gynecological and non-gynecological procedures, and to assess women's perceptions of vNOTES, …