Endometriosis (EMs) is a chronic gynecological disease with poorly understood pathogenesis. This study integrated lipidomics and transcriptomics to systematically investigate aberrant sphingolipid metabolism in EMs, aiming to identify pathogenic mechanisms …
Background/Objectives: Primary renal endometriosis with extrapelvic locations of endometriosis lesions is deemed extremely rare. Therefore, the aim of this review was to assess the current literature on renal endometriosis, encompassing …
Human papillomavirus (HPV) infection is a necessary but insufficient cause of cervical cancer (CC) and reflects a long-standing host-virus equilibrium shaped by immune control, viral persistence, and latency. The transition …
Endometriosis is a widespread gynecological disorder causing severe pain and infertility, with diagnosis currently relying on slow, costly, and risky laparoscopy. This highlights the critical need for non-invasive imaging diagnostics …
Endometriosis is a chronic, oestrogen-dependent inflammatory disorder associated with elevated systemic oxidative stress. Current medical therapies are limited by significant side effects and high recurrence rates, underscoring the need for …
Oocyte quality is the primary determinant of success in assisted reproductive technologies (ART), and mitochondrial dysfunction is increasingly recognized as a central mediator of poor oocyte competence across advanced maternal …
Ovarian endometriomas are commonly assessed according to cyst size and laterality, anatomical features that have long been regarded as indicators of disease severity and potential ovarian compromise. Consequently, these characteristics …
Endometriosis affects approximately 10% of women of reproductive age and is associated with infertility in up to half of those diagnosed. Despite decades of research, the molecular basis of its …
Decidualized ovarian endometriomas are benign lesions that can closely mimic ovarian malignancy on ultrasound. Correctly identifying them is crucial to avoid unnecessary interventions and associated adverse fetal-maternal outcomes. A systematic …
Unexplained Recurrent Pregnancy Loss and Emerging Endometrial Biology: A Clinically Oriented Narrative Review Cureus