E2F1 downregulation promotes lipid droplet accumulation and endometriosis development through impaired MGLL-mediated lipid mobilization.
Endometriosis is a common gynecological disease in which lipid metabolic dysregulation has been increasingly implicated. However, the specific metabolic changes in ectopic lesions and stromal cells remain poorly understood. It …
Comparison of perioperative outcomes between laparoscopy and robotic-assisted surgery in the surgical treatment of endometriosis: a retrospective study.
Minimally invasive surgery is the gold standard for the surgical treatment of endometriosis. However, controversy remains in the literature regarding the perioperative benefits of robotic-assisted surgery compared to laparoscopic surgery, …
Transvaginal Strain Elastography Methodology in Deep Endometriosis: Narrative Review and Proposal of a Standardized Imaging Protocol.
Transvaginal strain elastography (SE) has emerged as a complementary technique to transvaginal ultrasound for deep endometriosis (DE) evaluation by exploiting tissue stiffness between lesions and surrounding structures. However, its clinical …
Use of symptom-reporting tools to support endometriosis identification and management in primary care: a realist synthesis.
Endometriosis affects 5-10% of women of reproductive age and is associated with chronic pain, infertility and reduced quality of life. Symptom Reporting Tools (SRTs) may support identification and management in …
Machine learning-assisted design of a novel crocin-loaded poloxamer 407/hyaluronic acid in situ forming hydrogel for endometriosis treatment: in vitro characterization and in vivo efficacy evaluation.
Our study focused on fabricating and characterizing a crocin in situ forming hydrogel for endometriosis treatment. An artificial neural network (ANN)-based machine learning (ML) approach was employed to determine the …