Endometriosis is a chronic, estrogen-dependent inflammatory disorder requiring long-term management strategies that balance efficacy with systemic safety. Although hormonal therapies remain the cornerstone of treatment, the optimal degree of estrogen …
Which patients with endometriosis suffer from diminished ovarian reserve as well as impaired embryo quality and therefore could benefit from medical freezing as part of fertility preservation strategies?
Endometriosis is a hormone-dependent chronic inflammatory disease associated with pain and infertility, remains diagnostically and therapeutically challenging due to its multifactorial nature. Molecular mechanisms of the dynamic changes during disease …
Stem cell-based models resembling murine blastocysts represent a useful system to investigate subsequent developmental processes. While existing cell lines derived from epiblast and trophectoderm can be aggregated to form 'blastoids', …
Endometriosis is a chronic gynecological disease characterized by the growth of endometrial-like tissue outside the uterus, leading to pelvic pain, infertility, and other major health complications. Though some studies have …
Endometriosis is a chronic gynecological disorder characterized by the presence of endometrium-like tissue outside the uterine cavity. It is most commonly found in the pelvic organs but may also occur …
Endometriosis is an estrogen-dependent disorder characterized by ectopic growth of endometrial tissue. There is a lack of effective biomarkers for early detection and revealing mechanisms of endometriosis. CSNK2A1 is a …
To challenge the perception that endometriosis uniformly regresses after menopause by presenting the case of repeated, pathology-confirmed symptomatic recurrences spanning two decades after menopause, and to emphasize key considerations for …
Endometriosis (EMs) is a chronic inflammatory disease characterized by ectopic endometrial growth. This study aimed to identify and analyze potential signatures of pyroptosis-related genes in EMs.
Anxiety is heritable and exists on a continuum, with symptoms ranging from adaptive threat response to clinical disorder. Here we performed a genome-wide association meta-analysis of generalized anxiety symptom severity …