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Exploring biopsychosocial health outcomes in endometriosis and endometriosis with co-occurring irritable bowel syndrome - A prospective cohort study.

To date there has been limited exploration of the impact of endometriosis with co-occurring irritable bowel syndrome (IBS) type symptoms on biopsychosocial health outcomes and wellbeing. This study aimed to …

Published: Oct. 8, 2025, midnight
TGFB1/SMAD3-Driven Macrophage-Myofibroblast Transition Promotes Fibrosis Progression in Endometriosis.

Endometriosis is a chronic gynecological disorder characterized by progressive fibrosis, which is closely associated with clinical symptoms such as dysmenorrhea and infertility. While myofibroblast activation is central to fibrogenesis, the …

Published: Oct. 7, 2025, midnight
Does age influence surgical technique in bowel endometriosis? A multicenter analysis of 1547 cases.

To evaluate whether patient age influences the complexity of the surgical approach for bowel endometriosis, including the technique performed and the route of specimen extraction. Methods: Retrospective, multicenter observational study, …

Published: Oct. 7, 2025, midnight
Fallopian tubes influences sperm selection and fertilization success.

This study investigates the proteomic profile of the fallopian tube following exposure to human sperm, with a focus on its role in sperm capacitation, final sperm maturation, successful fertilization, and …

Published: Oct. 6, 2025, midnight
Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System.

The ascent of novel alternative methods (NAMs) in drug development spotlights the dual needs for improved biological fidelity to in vivo along with reproducibility, especially in regulatory applications. The need …

Published: Oct. 6, 2025, midnight
Molecular Pathogenesis of Ovarian Endometrioma: Mechanistic Insights and Therapeutic Implications.

Ovarian endometrioma (OMA), the most prevalent and clinically consequential subtype of endometriosis, represents a chronic inflammatory disorder characterized by ectopic endometrial-like lesions. This condition manifests as progressive dysmenorrhea, ovarian reserve …

Published: Oct. 4, 2025, midnight
Validity and reliability testing of the Pelvic Pain Impact Questionnaire.

The aim of this study was to conduct a Hungarian cross-cultural adaptation and assess the reliability and validity of the Pelvic Pain Impact Questionnaire (PPIQ) in women with chronic pelvic …

Published: Oct. 3, 2025, midnight
Kuntai Capsule for the Treatment of Menopausal Symptoms Induced by GnRH-a Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Gonadotropin-releasing hormone agonists (GnRH-a) often induce menopausal symptoms, negatively affecting women's psychological, emotional, and physical health. Kuntai capsule is widely used in clinical practice to alleviate various menopausal symptoms. Exploring …

Published: Oct. 3, 2025, midnight
Psychological, Symptom-Related, and Lifestyle Predictors of Health-Related Quality of Life in Hungarian Women with Endometriosis.

Background: This study was a cross-sectional online survey aimed at examining health-related quality of life and the effect of different symptoms and lifestyle factors on health-related quality of life in …

Published: Oct. 3, 2025, midnight
Equity and Data Gaps in Real-World Endometriosis Management.

Published: Oct. 2, 2025, midnight
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