To compare clinical features, treatment responses, and survival outcomes between endometriosis-associated ovarian cancer (EAOC) and high-grade serous ovarian carcinoma (HGSOC), with a focus on platinum resistance.
Gynecological conditions including endometriosis, polyendocrine metabolic ovarian syndrome and malignancies cause widespread chronic morbidity and infertility, yet translating genetic discoveries into biological mechanisms remains challenging. We propose a framework integrating …
Endometriosis is a debilitating, estrogen-dependent gynecological disorder characterized by profound diagnostic delays due to clinical reliance on invasive laparoscopy. Developing noninvasive, point-of-care biomarker assessment remains a critical yet unmet medical …
Background and Objectives: Endometriosis is a chronic inflammatory disease associated with impaired fertility, but the extent to which its systemic inflammatory profile differs from that observed in infertile women without …
To investigate the mechanisms by which Shaofu Zhuyu decoction (SFZYD, ) modulates fibrosis in a mouse model of endometriosis.
FemTech continues to evolve and advance despite persistent research and funding gaps. In this News and Perspectives article, JMIR Correspondent Jenny Castillo Cato reports on an innovative, cross-disciplinary research project …
While endometriosis is thought to be a heterogeneous disease, the pathophysiologic heterogeneity across the three visualized lesion macrophenotypes (i.e., superficial peritoneal endometriosis(SPE) lesions, endometriomas, and deep lesions) remains unclear.
Endometriosis (EM) is a chronic, inflammatory gynaecological disorder defined by the presence of endometrial-like tissue outside the uterine cavity, most frequently affecting the ovaries, peritoneum, and uterosacral ligaments. Despite its …
The objective of this study is to evaluate differences in patient-reported symptom outcomes among individuals with postural orthostatic tachycardia syndrome (POTS) stratified by the presence or absence of co-occurring endometriosis.
Endometriosis and irritable bowel syndrome (IBS) are chronic pain disorders that frequently coexist and share key pathophysiological features, including neuroinflammation, visceral hypersensitivity, peripheral sensitization, and central sensitization. Emerging evidence suggests …