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Identification of common diagnostic genes and molecular pathways in endometriosis and systemic lupus erythematosus by machine learning approach and in vitro experiment.

Growing research suggests that endometriosis and systemic lupus erythematosus (SLE) are both chronic inflammatory diseases and closely related, but no studies have explored their common molecular characteristics and underlying mechanisms. …

Published: Jan. 1, 2025, midnight
Surface Molecular Markers for the Isolation of Viable Fibroblast Subpopulations in the Female Reproductive Tract: A Comprehensive Review.

Advancements in single-cell analyzis technologies, particularly single-cell RNA sequencing (scRNA-seq) and Fluorescence-Activated Cell Sorting (FACS), have enabled the analyzis of cellular diversity by providing resolutions that were not available previously. …

Published: Dec. 30, 2024, midnight
A machine learning-based immune response signature to facilitate prognosis prediction in patients with endometrial cancer | Scientific Reports - Nature.com

A machine learning-based immune response signature to facilitate prognosis prediction in patients with endometrial cancer | Scientific Reports Nature.com

Published: Dec. 28, 2024, 2:37 a.m.
A machine learning-based immune response signature to facilitate prognosis prediction in patients with endometrial cancer - Nature.com

A machine learning-based immune response signature to facilitate prognosis prediction in patients with endometrial cancer Nature.com

Published: Dec. 28, 2024, 2:37 a.m.
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits.

Endometriosis is a common gynecologic condition that causes chronic life-altering symptoms including pain, infertility, and elevated cancer risk. There is an urgent need for new non-hormonal targeted therapeutics to treat …

Published: Nov. 22, 2024, midnight
A Comprehensive Review of Advanced Diagnostic Techniques for Endometriosis: New Approaches to Improving Women's Well-Being.

According to the World Health Organization (WHO), endometriosis affects roughly 10% (190 million) of reproductive-age women and girls in the world (2023). The diagnostic challenge in endometriosis lies in the …

Published: Nov. 14, 2024, midnight
Identification of a disulfidptosis-related genes signature for diagnostic and immune infiltration characteristics in endometriosis | Scientific Reports - Nature.com

Identification of a disulfidptosis-related genes signature for diagnostic and immune infiltration characteristics in endometriosis | Scientific Reports Nature.com

Published: Oct. 29, 2024, 9:31 a.m.
Identification of a disulfidptosis-related genes signature for diagnostic and immune infiltration characteristics in endometriosis.

Endometriosis (EMs) is the prevalent gynecological disease with the typical features of intricate pathogenesis and immune-related factors. Currently, there is no effective therapeutic intervention for EMs. Disulfidptosis, the cell death …

Published: Oct. 29, 2024, midnight
Dissecting the cell microenvironment of ovarian endometrioma through single-cell RNA sequencing.

Ovarian endometrioma (OE), also known as "chocolate cysts," is a cystic mass that develops in the ovaries due to endometriosis and is a common gynecological condition characterized by the growth …

Published: Oct. 28, 2024, midnight
Cross-Tissue Regulatory Network Analyses Reveal Novel Susceptibility Genes and Potential Mechanisms for Endometriosis.

Endometriosis (EMT) is a common gynecological disease with a strong genetic component, while its precise etiology remains elusive. This study aims to integrate transcriptome-wide association study (TWAS), Mendelian randomization (MR), …

Published: Oct. 26, 2024, midnight
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