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Serum Galectin-1 as a Diagnostic Biomarker in Endometriosis: A Prospective Longitudinal Study.

Endometriosis is a chronic condition characterized by the presence of endometrial-like tissue outside the uterine cavity. It affects ~10% of reproductive-aged individuals and is associated with dysmenorrhea and infertility. Although …

Published: Oct. 25, 2025, midnight
Ferroptosis in the Ovarian Follicular Microenvironment: A Redox-Dependent Cell Death Pathway with Emerging Roles in PCOS, Oocyte Quality, and IVF Outcomes.

Ferroptosis is a novel kind of regulated cell death that occurs when redox equilibrium is disrupted, leading to iron-dependent lipid peroxidation. Ferroptosis is defined by the buildup of deleterious lipid …

Published: Oct. 25, 2025, midnight
Diagnostic Delays and Economic Burden in Japanese Women with Endometriosis: A Cross-Sectional Analysis.

This study investigates the association between diagnostic delay (DD) and clinical and behavioral variables among Japanese women with endometriosis, and explores an optimal cut-off point distinguishing short and long DD.

Published: Oct. 25, 2025, midnight
HMGB-1 Increases Proinflammatory Reaction via TLR4 in Human Granulosa Cells of Endometriosis.

Background/Objectives: Oxidative stress is a critical factor in the development and progression of endometriosis. Granulosa cells, which reside near oocytes in follicles, exhibit steroidogenic activity, and, consequently, influence oocyte quality. …

Published: Oct. 24, 2025, midnight
First birth rates after surgically verified subtypes of endometriosis-a national register study of 9,590 women from Finland.

To study first birth rates according to endometriosis subtype after surgical diagnosis among nulliparous women.

Published: Oct. 24, 2025, midnight
Targeting Steroid Receptor Coactivators for the Treatment of Benign Female Reproductive Disorders.

Steroid receptor coactivators (SRCs) are master regulators of nuclear receptor signaling and play essential roles in female reproductive physiology. By integrating steroid hormone signaling with growth factors and metabolic pathways, …

Published: Oct. 23, 2025, midnight
Improving Diagnostic Yield in Peritoneal Endometriosis: Value of Additional Level Sections and Sampling Protocols.

To evaluate whether deeper histologic sections and tissue-blocking practices improve the diagnosis of endometriosis in peritoneal biopsies. We retrospectively reviewed 148 peritoneal biopsy cases with clinical suspicion of endometriosis from …

Published: Oct. 23, 2025, midnight
Primary Invasive Squamous Cell Carcinoma of the Vagina Presenting Three Decades After Total Hysterectomy for Benign Endometriosis: A Case Report.

A 57-year-old woman (G2P2) with a history of total hysterectomy for endometriosis 30 years earlier, presented for a routine gynecological examination without complaints. Speculum examination revealed an erythematous, raised plaque …

Published: Oct. 23, 2025, midnight
Exploring the Early Endometrial-Blastocyst Interactome in Endometriosis: An Integrative Study.

Background: Background: Endometriosis affects 10% of women of reproductive age. Despite the well-known association between endometriosis and infertility, the mechanisms underlying this association remain to be elucidated. Methods: Implantation and …

Published: Oct. 23, 2025, midnight
Comparison of sociodemographic factors, lifestyle, and gastrointestinal symptoms between patients with endometriosis and IBS.

Endometriosis and Irritable bowel syndrome (IBS) are two common diseases with overlapping symptomatology, causing confusion and delay in the diagnostic process. The objective of this study was to identify differences …

Published: Oct. 21, 2025, midnight
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