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The Diagnostic Odyssey of a Biochemically Confirmed Case of ML II: The First Western Patient With LYSET Deficiency.

The LYSET gene encodes the LYSET transmembrane protein, which regulates lysosome biogenesis by activating the mannose-6-phosphate (M6P) pathway. This is an autosomal recessive, ultrarare, and severe progressive skeletal dysplasia with …

Published: March 20, 2026, midnight
Is endometriosis a progressive disease?

Whether endometriosis is a progressive disease remains debated. Central to this debate is understanding the natural history of endometriotic lesions, which are essentially wounds undergoing repeated tissue injury and repair. …

Published: March 20, 2026, midnight
Exposure to Green Light-emitting Diodes Alleviates Endometriosis-associated Pain in Mice with Induced Deep Endometriosis.

Published: March 19, 2026, midnight
Robotic interposition of the mesorectum during low anterior resection of the rectum for endometriosis using tissue perfusion assessment with indocyanine green.

Rectal endometriosis is a serious disease, and its surgical treatment belongs among demanding procedures, often requiring a multidisciplinary approach. It is associated with a significant risk of peri- and postoperative …

Published: March 18, 2026, midnight
SGLT2 Inhibitors and Mortality in Endometriosis With Type 2 Diabetes: A Propensity-Matched Analysis.

Endometriosis is increasingly recognized as a systemic inflammatory condition associated with adverse cardiovascular events, yet glucose-lowering drug selection in this population is not evidence-based.

Published: March 18, 2026, midnight
Laparoscopic Retrograde Hysterectomy: A Review of Techniques, Indications, and Outcomes.

Laparoscopic retrograde hysterectomy (LRH) represents an innovative minimally invasive approach for managing complex pelvic pathology where conventional techniques are contraindicated. This review synthesizes current evidence regarding its techniques, indications, and …

Published: March 18, 2026, midnight
Repeatedly occurring retrograde menstruation intensifies central sensitization driven by neuroinflammation in endometriosis models.

This study investigated how chronic pelvic pain (CPP) develops using rhesus macaques with naturally occurring endometriosis and a multiple-lesion induction mouse model (MIM), as repeated retrograde menstruation is considered an …

Published: March 17, 2026, midnight
Intra-Patient Variability in the Number of Retrieved Oocytes and Ovarian Response Categories Between Consecutive IVF Cycles.

To examine intra-patient variability in retrieved oocyte numbers across consecutive in-vitro fertilization (IVF) ovarian stimulation (OS) cycles with an identical OS protocol.

Published: March 17, 2026, midnight
Xanthogranulomatous Oophoritis Associated With Chronic Endometriosis: A Clinical Observation.

Xanthogranulomatous oophoritis (XGO) is a rare chronic inflammatory con-dition that can mimic ovarian malignancy both clinically and radiologically. It is characterized by foamy histiocytes and inflammatory infiltrates, often leading to …

Published: March 17, 2026, midnight
Safety and Reproductive Outcomes of Minimally Invasive Nerve-Sparing Surgery for Deep Endometriosis in Infertile Women: A One-Year Follow-Up Study.

Background/Objectives: Deep endometriosis is a chronic inflammatory disease that significantly affects fertility. The objective was to evaluate the magnitude of the effect of minimally invasive nerve-sparing complete excision of endometriosis …

Published: March 17, 2026, midnight
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