Maternal chronic conditions are implicated as risk factors for congenital anomalies, but few studies have assessed reproductive conditions such as endometriosis. Given the association between endometriosis and infertility requiring fertility …
Endometriosis, a chronic disease that affects about 10% of women of reproductive age, is characterized by severe pain and growth of endometrium-like tissues outside the uteri. Although several theories have …
Fibroblast growth factor receptor 2 (FGFR2) has emerged as a highly promising therapeutic target due to its critical role in the pathogenesis and progression of endometriosis. To date, a variety …
This case report describes a rare presentation of primary periumbilical endometriosis, also known as Villar's nodule, highlighting the diagnostic difficulties and the importance of maintaining clinical suspicion. A 37‑year‑old woman …
Endometriosis is a chronic gynecological disorder defined by the growth of endometrial-like tissue outside the uterus, driven by estrogen-dependent inflammation and progressive fibrosis. According to available data, remodeling and persistent …
This study aims to develop and validate a Multi-Dimensional Computational Screening (MDCS) strategy to identify bioactive components by jointly considering target affinity, exposure potential, and safety, using Liangdi decoction (LDD) …
Endometriosis is a chronic, estrogen-dependent gynecological disorder affecting approximately 10% of women worldwide that can cause pelvic pain, lead to infertility, and impair quality of life. Whether the condition elevates …
Background: Endometriosis is a chronic, estrogen-dependent inflammatory disorder affecting millions of women worldwide and constitutes a major cause of chronic pelvic pain and reduced quality of life. Increasing evidence suggests …
Investigating the genetic influence of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) on key inflammatory biomarkers-Interleukin-1β, Interleukin-6, and high-sensitivity C-reactive protein (hsCRP) and to evaluate their association with disease progression …
The study explored the mechanism of Dan'e-fukang soft extract in treating endometriosis (EMs) through network pharmacology. The main active ingredients of Dan'e-fukang soft extract were analyzed based on the traditional …