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From biomolecules to breakthroughs: exosomes as next-generation theranostics in female infertility.

Female infertility and reproductive disorders represent a significant global health challenge, with complex etiologies often linked to impaired cellular communication, inflammation, and tissue dysfunction. Exosomes (EXOs), nanosized extracellular vesicles laden …

Published: Oct. 1, 2025, midnight
Deep pelvic endometriosis: clinical features, diagnosis, and treatment - a comprehensive review.

Deep infiltrative endometriosis (DIE) is characterized by the infiltration of endometrial tissue into the pelvic organs, such as the rectovaginal septum, utero-ovarian, and uterosacral ligaments. Bowel involvement occurs in approximately …

Published: Sept. 30, 2025, midnight
Should patients undergo endometrioma surgery before IVF/ICSI? a retrospective study with propensity score matching.

Does surgical management of ovarian endometriomas improve in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI)?

Published: Sept. 30, 2025, midnight
Relation of Endometrioma and Deep Infiltrating Endometriosis Surgery on Ovarian Reserve: A Large Single-Centre, Cross-Sectional Study.

There is a lack of reliable data or evidence-based protocol for the management of deep infiltrating endometriosis (DIE) lesions in reproductive age women. This study examines ovarian reserves in women …

Published: Sept. 30, 2025, midnight
Clinicopathological Characteristics and Oncologic Outcomes of Endometrioid Ovarian Carcinoma: A Retrospective Study from a Tertiary Cancer Centre.

Background/Objectives: To evaluate the clinicopathological features, treatment, and survival outcomes and to identify independent prognosticators for recurrence and mortality in patients with endometrioid ovarian cancer. Methods: The medical records of …

Published: Sept. 28, 2025, midnight
Big data analysis reveals miR-874 as a suppressor and therapeutic target in the progression from endometriosis to ovarian cancer.

Published: Sept. 26, 2025, midnight
FIGO committee opinion: Environmental drivers of gynecologic and reproductive health.

This FIGO committee opinion paper addresses the growing body of evidence linking environmental exposures to common gynecologic and reproductive conditions across the life course. From adolescence through menopause, women are …

Published: Sept. 26, 2025, midnight
From gut to gamete: how the microbiome influences fertility and preconception health.

Global fertility rates continue to decline despite advancements in assisted reproductive technologies, highlighting a significant gap in our understanding of the mechanisms underlying preconception physiology. In this commentary, we review …

Published: Sept. 26, 2025, midnight
Mesenchymal stem cells: opening a new chapter in the treatment of gynecological diseases.

In recent years, mesenchymal stem cells (MSCs) have garnered significant attention as promising therapeutic tools for various diseases. To date, over ten MSC-based therapies have been approved and marketed worldwide, …

Published: Sept. 26, 2025, midnight
Long-term health consequences of childhood adverse events: A narrative review.

"Adverse childhood events" or childhood adversity is a term often used to describe trauma and sources of stress during childhood or adolescence. Childhood adversity may negatively affect multiple aspects of …

Published: Sept. 26, 2025, midnight
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