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Maternal and fetal outcomes among pregnant women with endometriosis.

Endometriosis, a condition in which endometrial-like tissue grows outside of the uterus, is a common disorder among women of reproductive-age. The objective of the study is to examine the associations …

Published: Nov. 6, 2024, midnight
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice.

Endometriosis is a debilitating and painful gynecological inflammatory disease affecting up to 15% of women and transgender men. Current treatments are ineffective for a substantial proportion of patients, underscoring the …

Published: Nov. 6, 2024, midnight
Digital Twin of the Female Pelvic Floor.

Digital twin technology, originally developed for intricate physical systems, holds great potential in women's healthcare, particularly in the management of pelvic floor disorders. This paper delves into the development of …

Published: Nov. 6, 2024, midnight
Adenomyosis-associated infertility: an update of the immunological perspective.

Adenomyosis is characterized by the invasion of endometrial glands and stroma into the myometrium. Its clinical manifestations often include dysmenorrhoea, excessive menstrual bleeding and infertility. Reduced pregnancy and live birth …

Published: Nov. 6, 2024, midnight
How does surgery influence female sexuality in patients with endometriosis compared to those with other benign gynecological conditions?

Endometriosis is a chronic, estrogen-dependent, benign condition, affecting 10-15% of women of reproductive age. It is associated with a prevalence of sexual dysfunction that is nearly twice as high as …

Published: Nov. 5, 2024, midnight
Is Osteopontin a Reliable Biomarker for Endometriosis?

This study aimed to evaluate the concentration of osteopontin in peritoneal fluid and plasma as potential biomarkers for diagnosing endometriosis. Osteopontin levels were measured using surface plasmon resonance imaging (SPRI) …

Published: Nov. 5, 2024, midnight
Robotic Assisted Lapendoscopic Single-Site Surgery for Ileal Deep Endometriosis. A Case Report and Review of Literature.

The prevalence of deep endometriosis invading the bowel is unknown but has been estimated to affect between 3.8% and 37% of women with endometriosis. The most common locations of bowel …

Published: Nov. 4, 2024, midnight
Chronic overlapping pain conditions and nociplastic pain.

Chronic overlapping pain conditions (COPCs) are a subset of chronic pain conditions commonly comorbid with one another and more prevalent in women and individuals assigned female at birth (AFAB). Pain …

Published: Nov. 4, 2024, midnight
Overexpressed nicotinamide N‑methyltransferase in endometrial stromal cells induced by macrophages and estradiol contributes to cell proliferation in endometriosis.

Endometriosis, an estrogen-dependent chronic inflammatory condition, afflicts reproductive-aged women. However, the underlying pathological mechanisms remain to be elucidated. Nicotinamide N-methyltransferase (NNMT) is a critical enzyme involved in cellular metabolism and …

Published: Nov. 3, 2024, midnight
miR-193b-5p and miR-374b-5p Are Aberrantly Expressed in Endometriosis and Suppress Endometrial Cell Migration In Vitro.

(1) Background: Endometriosis is a highly prevalent gynecological disease affecting 10% of women of reproductive age worldwide. miRNAs may play a role in endometriosis, though their exact function remains unclear. …

Published: Nov. 3, 2024, midnight
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