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Influence of endometrial nerve fibers and hormones on pain in women with endometriosis.

The mechanisms behind endometriosis-related pain are not yet fully understood. To determine if there is a difference in the density of endometrial nerve fibers between women with endometriosis and healthy …

Published: April 1, 2025, midnight
In utero exposure to synthetic sex hormones and their multigenerational impact on neurodevelopmental disorders: Endocrine disruptors as neuroendocrine disruptors.

Synthetic sex hormones, estrogens and/or progestogens, have been widely administered without sufficient long-term studies for decades to millions of pregnant women around the world and although most were banned in …

Published: April 1, 2025, midnight
SIRT7 facilitates endometrial cancer progression by regulating PTEN stability in an estrogen-dependent manner - Nature.com

SIRT7 facilitates endometrial cancer progression by regulating PTEN stability in an estrogen-dependent manner Nature.com

Published: March 27, 2025, 6:35 a.m.
Ferroptosis in Endometriosis: Traditional Chinese Medicine Interventions and Mechanistic Insights.

Endometriosis (EMS) is a chronic, estrogen-dependent inflammatory disease affecting 5-10% of women of reproductive age, characterized by the growth of endometrial tissue on the outside of the uterus. The dysregulation …

Published: March 27, 2025, midnight
A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression.

Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertility are urgently required. We thus …

Published: March 26, 2025, midnight
Utilising Human Myometrial and Uterine Fibroid Stem Cell-Derived Three Dimentional Organoids as a Robust Model System for Understanding the Pathophysiology of Uterine Fibroids.

Uterine fibroids (UFs) are the most common benign gynecologic tumours affecting women of reproductive age. This study aims to deepen the understanding of UFs complex aetiology through harnessing the power …

Published: March 20, 2025, midnight
Sleep Health and Psychological Wellbeing in Adult Women: A Specific Focus on Endometriosis-A Survey Study.

Background: Endometriosis is a chronic, oestrogen-sensitive inflammatory disease, which can have a significant impact on women's wellbeing. Nevertheless, the sleep health of this population has been poorly investigated. This exploratory …

Published: March 19, 2025, midnight
Atypical Endometriosis - An Overview of the Issue and Personal Experiences.

Endometriosis is a chronic, estrogen-dependent, inflammatory disease characterized by the growth of endometriotic tissue outside the uterus. Among the wide spectrum of clinical manifestations of endometriosis, chronic pelvic pain, dysmenorrhea, …

Published: March 17, 2025, 12:08 a.m.
Therapeutic Effects and Mechanisms of Alcohol Extracts from Polygala fallax Hemsl on Endometriosis in Rats.

Endometriosis is a chronic estrogen-dependent inflammatory disease that significantly affects women's health. Polygala fallax Hemsl. (PFH), a traditional Zhuang medicine, has been frequently used for gynecological disorders. This study investigated …

Published: March 14, 2025, midnight
Effect of dietary patterns and nutritional supplementation in the management of endometriosis: a review.

Endometriosis is an estrogen-dependent chronic inflammatory disease which causes dysmenorrhea, chronic pelvic pain, and infertility in women of childbearing age, significantly impacting their quality of life and physical and mental …

Published: March 12, 2025, midnight
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