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Microbiota insights in endometriosis.

Endometriosis affects approximately 10% of women of reproductive age and is characterized by the presence of endometrial-like tissue outside the uterine cavity, leading to chronic pelvic pain, infertility, and a …

Published: Dec. 5, 2025, midnight
Sun's Bushen Huayu Formula Restores Fertility in Endometriosis by Modulating Th1 and Th2 Cytokine Balance in Clinical and Animal Models.

Endometriosis (EMs) is a common gynecological disorder frequently associated with infertility, yet the underlying immune mechanisms remain poorly understood. Sun's Bushen Huayu Formula (BSHYF) has been clinically applied to improve …

Published: Dec. 5, 2025, midnight
The Investigation of Vitamin D and Menstrual Cycles Trial (the inVitD Trial): A clinical trial of vitamin D supplementation on the hypothalamic-pituitary-ovarian axis.

While there is evidence that vitamin D deficiency is associated with long menstrual cycles, delayed ovulation, and reduced fertility, it is yet unknown if increasing vitamin D levels can regulate …

Published: Dec. 4, 2025, midnight
Ethanol sclerotherapy for endometriomas: a fertility-preserving alternative.

Endometriomas are a common manifestation of endometriosis in women of reproductive age and pose a clinical challenge due to their association with pain, infertility, and compromised ovarian reserve. Surgical removal …

Published: Dec. 4, 2025, midnight
Infertility management in patients with bowel endometriosis: the current landscape and the promise of randomised trials: a narrative review.

The management of infertility in women with bowel endometriosis remains a significant clinical challenge. The two primary therapeutic approaches include first-line medically assisted reproduction (MAR) and primary bowel surgery, with …

Published: Dec. 3, 2025, midnight
Sexual Functioning and Quality of Life Among Women With Endometriosis: A French Cross-Sectional Survey.

Evidence suggests that symptoms of endometriosis related to sexual dysfunction can disrupt intimate and sexual partnerships. The goal of this study was to understand the association between quality of life …

Published: Dec. 3, 2025, midnight
Emerging roles and therapeutic potential of tRNA-Derived small RNAs in reproductive system diseases: a review.

tRNA-derived small RNAs (tsRNAs) are a class of non-coding RNAs(ncRNAs) generated from precursor or mature tRNAs under stress conditions, such as starvation, hypoxia, or oxidative stress. They are broadly classified …

Published: Dec. 3, 2025, midnight
The role of pharmacotherapy in the treatment of endometriosis: an update.

Endometriosis is a chronic inflammatory condition affecting ~10% of reproductive-age individuals and contributing significantly to infertility, pain, and reduced quality of life. Since our 2020 review, new pharmacologic strategies, updated …

Published: Dec. 2, 2025, midnight
Histomorphometric characterization of the endometrium in mules (Equus mulus): An approach to endometritis/endometrosis.

Mules (Equus mulus), as sterile hybrids between mares and donkeys, present a unique uterine morphology and physiology that remains poorly characterized. This study provides the first histomorphometric evaluation and transcriptional …

Published: Dec. 2, 2025, midnight
ZMIZ1 and estrogen receptor α form an essential partnership in endometrial biology.

Estrogen receptor α (ESR1) is a pivotal regulator of endometrial homeostasis and reproductive function, yet the coregulators that fine tune its transcriptional activity remain incompletely defined. In this issue of …

Published: Dec. 1, 2025, midnight
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