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Activity-Selectivity of Flavonoid Derivatives in Endometriotic Cells.

Natural polyphenolics, more specifically flavonoids and derivatives, constitute chemically versatile scaffolds with a broad biological potential. In this study, different flavonoid derivatives (1-37) were assessed for cytotoxicity in Ishikawa and …

Published: Feb. 2, 2026, midnight
Innervation of the Uterus: An Anatomical Study With Application to Better Understanding Pelvic Pain in Women.

Pelvic pain has a significant impact on quality of life, especially when associated with benign pelvic diseases, such as endometriosis or chronic conditions leading to persistent discomfort. A substantial proportion …

Published: Feb. 1, 2026, midnight
Phthalate Metabolite, Mono(2-Ethyl-5-Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine-Fibroid-Associated Phenotypes in Myometrial Stem Cell-Derived 3D Organoids.

This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2-ethylhexyl) phthalate, on myometrial stem cells …

Published: Feb. 1, 2026, midnight
Hidden Burden of Fallopian Tube Endometriosis: Prevalence and Associations with Pelvic Pathology.

Background/Objectives: Fallopian tube endometriosis is frequently underreported due to its nonspecific presentation, limitations in imaging detection, and the fact that histologic diagnosis often requires the submission of the entire fallopian …

Published: Feb. 1, 2026, midnight
[Comparative analysis of clinicopathological and molecular characteristics between pure ovarian endometrioid carcinoma and synchronous endometrial and ovarian endometrioid carcinoma].

Objective: To investigate the differences in clinicopathological and molecular characteristics between pure ovarian endometrioid carcinoma (POEC) and synchronous endometrial and ovarian endometrioid carcinoma (SEOEC), aiming to provide a basis for …

Published: Jan. 31, 2026, midnight
Influence of Oxidative Stress-Mediated Inflammation on the Pathogenesis of Reproductive Disorders: Exploring the Benefits of Carnosine for Prevention and Treatment of Endometriosis.

Endometriosis is a chronic pathological condition characterized by the growth of endometrial-like tissue outside the uterine cavity and is frequently associated with severe pain, persistent inflammation, and fibrosis within the …

Published: Jan. 30, 2026, midnight
Chronic Pelvic Pain in Medical Education: A Needs Assessment of British Columbian Health Care Providers-in-Training.

Chronic pelvic pain (CPP) affects ∼15% of women and gender-diverse people, yet it is often dismissed by healthcare providers partly due to lack of related medical education. This brief communication …

Published: Jan. 30, 2026, midnight
Barriers affecting medication adherence to dienogest among patients with ovarian endometriosis: a qualitative study.

To explore barriers affecting medication adherence (e.g., missed doses, forgotten doses, or discontinuation) among patients with Ovarian Endometriosis (OE) using the Capability, Opportunity, Motivation - Behaviour (COM-B) behavioural change model …

Published: Jan. 30, 2026, midnight
Oral diclofenac potassium and intramuscular hyoscine-n-butyl bromide versus oral diclofenac potassium alone for pain relief during hysterosalpingography: a double blind randomized controlled trial.

Hysterosalpingography (HSG) is an important diagnostic tool in infertility, often associated with pain and tubal spasms, potentially resulting in false proximal tubal occlusions. This randomised controlled trial compared oral diclofenac …

Published: Jan. 29, 2026, midnight
The effect of tinzaparin sodium and leuprolide acetate in an experimental mouse model of endometriosis: The rol of the WNT/beta-catenin pathway.

Endometriosis is a benign condition driven by estrogen and inflammation in which endometrial-like tissue develops in ectopic locations. We aimed to determine whether non-steroidal agents acting on the WNT/beta-catenin signaling …

Published: Jan. 29, 2026, midnight
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