Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form …
Endometriosis is a heterogeneous pain condition with variable symptom expression. Abuse history has been associated with amplified pain, gastrointestinal symptoms, and central sensitization in varying populations; however, whether these effects …
Endometriosis (EMs) is a prevalent and challenging gynecological disease and current therapeutic outcomes are suboptimal. Traditional Chinese medicine (TCM) has numerous advantages in treating EMs. Bushen Wenyang Huayu Formula (BWHF), …
Endometriosis (EMs) is an estrogen-dependent, chronic inflammatory disorder characterized by immune microenvironment dysregulation, a critical factor in its pathogenesis. Despite existing therapies, limitations persist, highlighting the urgent need for innovative …
Background/Objectives: Endometriosis is a prevalent gynecological illness associated with chronic pain, inflammation, and infertility, as ectopic endometrial lesions are formed. No fully effective treatment is available, and the pathogenesis of …
This study aims to investigate the differences in response to dienogest (DNG) therapy among patients with 3 different phenotypes of endometriosis: ovarian endometrioma (OMA), superficial peritoneal endometriosis (SUP), and deep …
Fibrosis, angiogenesis and chronic inflammation are the intrinsic characteristics of endometriosis. It is accompanied by significant changes in the cell composition of both ectopic and eutopic endometrial tissues, occurring both …
Endometriosis is a major gynecologic health issue affecting ~10% of women and girls of reproductive age worldwide. Despite its high prevalence, no curative treatment exists. Early diagnosis and treatment are …
Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, …
Endometriosis (EMS) is a prevalent, inflammatory gynecological disorder with limited effective treatments and high recurrence rates. Given the central roles of inflammation, oxidative stress, pyroptosis, and angiogenesis in its pathogenesis, …