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Associations between 1400 metabolites and subtypes of endometriosis: a two-sample Mendelian randomisation study.

Endometriosis is a chronic inflammatory disease with a prevalence of approximately 10% in women of childbearing age. Metabolic pathways have been demonstrated by previous studies to be potential avenues for …

Published: Aug. 28, 2025, midnight
Growth Arrest-Specific Protein 6 Is Elevated in Endometriosis but Shows Poor Diagnostic Performance.

Growth arrest-specific protein 6 (GAS6) has an important role in regulating the immune system. Recent studies have revealed its association with the pathophysiology of endometriosis and identified GAS6 as one …

Published: Aug. 28, 2025, midnight
Gut Microbiota-Derived Acetate Ameliorates Endometriosis via JAK1/STAT3-Mediated M1 Macrophage Polarisation.

Endometriosis (EMs) is a common inflammatory disorder in women of reproductive age, severely impacting patients' quality of life and fertility. Current hormonal therapies offer limited efficacy, and surgical interventions often …

Published: Aug. 27, 2025, midnight
Endometriosis and its role in pouch patients: A matched-pair analysis.

Patients requiring ileoanal pouch (IPAA) are often women of reproductive age. Outcomes in pouch patients with endometriosis have not been described. This study aimed to assess the association of endometriosis …

Published: Aug. 27, 2025, midnight
A Cross-Sectional Study of Endometriosis Surgeries Across Obstetrics and Gynecology Subspecialties: Does Minimally Invasive Gynecologic Surgery (MIGS) Fellowship Training Make a Difference?

Objective The objective of this study was to compare the surgical approaches and postoperative outcomes of endometriosis surgeries performed by different obstetrics and gynecology (OBGYN) subspecialties: minimally invasive gynecologic surgery …

Published: Aug. 23, 2025, midnight
The endometriosis pain course: a randomized controlled trial of an internet-delivered psychological pain management program for endometriosis.

Limited research has examined psychological treatments for endometriosis-related chronic pain, despite its association with elevated disability, depression, and anxiety. Remotely delivered treatments have the potential to overcome barriers to access …

Published: Aug. 21, 2025, midnight
DRIVE-KG: Enhancing variant-phenotype association discovery in understudied complex diseases using heterogeneous knowledge graphs.

Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions, such as endometriosis which has been historically understudied despite …

Published: Aug. 21, 2025, midnight
Lipid accumulation products and endometriosis: A population-based study from NHANES.

To investigate the association between lipid accumulation product (LAP) and endometriosis using data from the National Health and Nutrition Examination Survey (NHANES), because lipid metabolism alterations and obesity have been …

Published: Aug. 18, 2025, midnight
Identification and Validation of Novel Combinatorial Genetic Risk Factors for Endometriosis across Multiple UK and US Patient Cohorts.

Endometriosis affects about 10% of women usually of reproductive age. It often has severe negative impacts on patients' quality of life, but the average time to a definitive diagnosis remains …

Published: Aug. 15, 2025, midnight
Detection of bacterial vaginosis-associated bacteria and outcomes during clinical gynaecological conditions using qPCR: A retrospective cohort study.

Endometriosis, chronic endometritis (CE), unexplained infertility (UI), and recurrent pregnancy loss (RPL) are gynecological conditions frequently associated with inflammation and alterations in the endometrial microbiome. The presence of bacterial vaginosis-associated …

Published: Aug. 15, 2025, midnight
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