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Ovarian Endometrioma Disrupts Oocyte-Cumulus Communication and Mitochondrial Function, With Melatonin Mitigating the Effects.

Ovarian endometrioma (OEM), a particularly severe form of endometriosis, is an oestrogen-dependent condition often associated with pain and infertility. The mechanisms by which OEM impairs fertility, particularly through its direct …

Published: Jan. 21, 2025, midnight
Mapping Human Uterine Disorders Through Single-Cell Transcriptomics.

Disruptions in uterine tissue function contribute to disorders such as endometriosis, adenomyosis, endometrial cancer, and fibroids, which all significantly impact health and fertility. Advances in transcriptomics, particularly single-cell RNA sequencing, …

Published: Jan. 21, 2025, midnight
A cRGD-modified liposome for targeted delivery of artesunate to inhibit angiogenesis in endometriosis.

Currently, hormonal therapy for endometriosis faces challenges in achieving a balance between treatment and preserving the chance of pregnancy. Therefore, the development of non-hormonal therapy holds significant clinical importance. Angiogenesis …

Published: Jan. 20, 2025, midnight
Heterotaxy syndrome, dextrocardia, ureteropelvic obstruction, endometriosis, and pulmonary hypertension in an adult with congenital heart defects: a case report.

Heterotaxia is characterized by an abnormal positioning of the thoracic and/or abdominal organs, resulting in various physiological and hemodynamic implications. Congenital heart disease involves structural irregularities in the heart or …

Published: Jan. 20, 2025, midnight
Improving Replication in Endometrial Omics: Understanding the Influence of the Menstrual Cycle.

The dynamic nature of human endometrial tissue presents unique challenges in analysis. Despite extensive research into endometrial disorders such as endometriosis and infertility, recent systematic reviews have highlighted concerning issues …

Published: Jan. 20, 2025, midnight
Understanding Deep Endometriosis: From Molecular to Neuropsychiatry Dimension.

Endometriosis is a widely spread disease that affects about 8% of the world's female population. This condition may be described as a spread of endometrial tissue apart from the uterine …

Published: Jan. 20, 2025, midnight
Hormone receptor profile of ectopic and eutopic endometrium in adenomyosis: a systematic review.

What is the hormone receptor profile of adenomyosis lesions in comparison to correctly located endometrium?

Published: Jan. 20, 2025, midnight
Management of Diaphragmatic Central Tendon Plays an Important Role in the Surgical Treatment of Catamenial Pneumothorax: A Case Report.

A 25-year-old unmarried woman with sex experience was referred to our hospital for the treatment of mild pneumothorax. On pneumothorax recurrence, thoracoscopy showed no cystic lesions on the visceral pleura …

Published: Jan. 20, 2025, midnight
Surgical management of umbilical endometrioma within an umbilical hernia.

A nulliparous woman in her 40s is referred to gynaecological oncology secondary to umbilical pain and bleeding with menses. Examination revealed a blood-filled cystic mass within an umbilical hernia consistent …

Published: Jan. 19, 2025, midnight
Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses.

This study aimed to assess the causal relationship between lipidome and female reproductive diseases (FRDs) using an advanced series of Mendelian randomization (MR) methods. This study utilized genome-wide association study …

Published: Jan. 19, 2025, midnight
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