Rheumatic heart disease (RHD) remains the leading cause of acquired valvular heart disease in low- and middle-income countries, affecting an estimated 40 million individuals and disproportionately affecting children and young …
Endometriosis is a chronic, estrogen-dependent inflammatory disease that causes debilitating pain and significantly impairs quality of life. Due to its anti-inflammatory and immunomodulatory properties, vitamin D has been proposed as …
Endometriosis is a chronic inflammatory and estrogen-dependent disease in which oxidative stress, immune dysregulation, and lesion-supportive microenvironmental signaling contribute to lesion development. N-acetylcysteine (NAC), a glutathione-replenishing and redox-modulating agent, has …
Endometriosis is a chronic inflammatory condition that can result in chronic pain through complex nociceptive, neuropathic, and nociplastic pathways. This article provides a comprehensive background on endometriosis as well as …
Dysmenorrhea is the most common gynaecological condition in women of reproductive age. Approximately 90% of cases are primary dysmenorrhea (PDM) which is not associated with underlying pathology. Dysmenorrhea can have …
Endometriosis is a multifactorial, chronic inflammatory disorder that affects a substantial proportion of women during their reproductive years and is frequently associated with pelvic pain and infertility. Accumulating evidence suggests …
The survival of ectopic endometrial lesions in endometriosis critically depends on their ability to evade immune recognition and clearance by the host, a process known as immune evasion. Recent studies …
Endometriosis affects about 10% of reproductive-age women, causing pelvic pain and infertility. Its progression involves angiogenesis and neurovascular innervation, mediated by vascular endothelial growth factor (VEGF) and brain-derived neurotrophic factor …
Endometriosis is a chronic inflammatory disease that affects around 10% of women of reproductive age and is frequently associated with infertility. Despite its high prevalence in assisted reproductive technology (ART) …
The etiopathogenesis of endometriosis-related infertility remains under investigation, including in women with endometriomas. Oocyte quality is believed to play an important role in the impairment of natural fertility in these …