Sex-related differences influence key biological processes relevant to biomaterials research, including tissue regeneration, immune response, drug metabolism, and relevant diseases. Despite increasing recognition of sex as a critical biological variable, …
In mammals, insulin-like peptide 3 (INSL3) and its cognate receptor (RXFP2) are reported to be essential regulators of male reproductive physiology. It is also believed that INSL3/RXFP2 signaling has a …
Pelvic inflammatory disease (PID) encompasses a broad range of infection-induced inflammatory disorders of the female upper genital tract, commonly caused by ascending sexually transmitted infections. Diagnosis is often challenging because …
Endometriosis is a disorder characterized by the presence of endometrial tissue outside the uterus, leading to dyspareunia, chronic pelvic pain, dysuria, and infertility. The latter has been related to implantation …
The Ras homolog gene family member A (RhoA) is a small GTPase. RhoA plays major roles in cytoskeletal regulation, transcriptional control, and cell cycle maintenance. RhoA is widely expressed in …
Enteric fever is a multisystem febrile illness caused by Salmonella enterica subspecies enterica serovar Typhi, Paratyphi A, B and C. It is usually transmitted through contaminated food and water. The …
The interplay between the gut microbiome and reproductive health has gained increasing attention in recent years. Emerging research suggests that imbalances in the gut microbiome may impact reproductive function through …
Menopause-related endocrinological shifts are linked to sexual dysfunction, and women with endometriosis exhibit lower Female Sexual Function Index (FSFI) scores, indicating impaired sexual well-being.
Synthetic sex hormones, estrogens and/or progestogens, have been widely administered without sufficient long-term studies for decades to millions of pregnant women around the world and although most were banned in …
The objective of this study was to evaluate the prevalence and impact of female sexual dysfunction and sexual distress in women with endometriosis. This retrospective, analytical, observational study included patients …