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Systemic Immune and Tumor Marker Profiles in Ovarian and Deep Infiltrating Endometriosis: Associations with Disease Severity and Symptom Burden.

Endometriosis is a chronic, estrogen-dependent inflammatory disease with heterogeneous clinical manifestations and uncertain systemic immune involvement. This study aimed to characterize peripheral immune profiles and circulating tumor markers in women …

Published: Oct. 1, 2025, midnight
From biomolecules to breakthroughs: exosomes as next-generation theranostics in female infertility.

Female infertility and reproductive disorders represent a significant global health challenge, with complex etiologies often linked to impaired cellular communication, inflammation, and tissue dysfunction. Exosomes (EXOs), nanosized extracellular vesicles laden …

Published: Oct. 1, 2025, midnight
Deep pelvic endometriosis: clinical features, diagnosis, and treatment - a comprehensive review.

Deep infiltrative endometriosis (DIE) is characterized by the infiltration of endometrial tissue into the pelvic organs, such as the rectovaginal septum, utero-ovarian, and uterosacral ligaments. Bowel involvement occurs in approximately …

Published: Sept. 30, 2025, midnight
Analysis of diagnostic apoptosis-related biomarkers and immune cell infiltration characteristics in endometriosis by integrating bioinformatics and machine learning.

Endometriosis (EMs) is a chronic disease affecting millions of women worldwide, yet its pathogenesis remains unclear, and current diagnostic methods are limited. This study based on the EMs dataset from …

Published: Sept. 29, 2025, midnight
Influence of Complex Disease on the Accuracy of Transvaginal Ultrasound Diagnosis of Uterosacral Ligament Endometriosis.

To assess the impact of complex disease states, including pouch of Douglas (POD) obliteration and deep endometriosis (DE) of the bowel, on the diagnostic accuracy of transvaginal ultrasound (TVUS) for …

Published: Sept. 28, 2025, midnight
Endometriosis Diagnostic Delay and Its Correlates: Results from the ComPaRe-Endometriosis Cohort.

Background: An average time to diagnosis of 7 years is commonly described for endometriosis; diagnostic delay for adenomyosis is unknown. This cross-sectional study aimed to describe diagnostic delay for endometriosis …

Published: Sept. 26, 2025, midnight
The Baffling Diagnosis of a Rare Case of Polypoid Endometriosis: Neoplasm Mimicking in a Young Pregnant Woman-A Case Report and Literature Review.

Background: Polypoid endometriosis is a rare variant of endometriosis that presents as a tumorous mass, making it difficult to differentiate it from a malignant tumor. It usually occurs in perimenopausal …

Published: Sept. 26, 2025, midnight
A narrative review of Catamenial dermatology: A glimpse into the menstrual symphony.

The menstrual cycle induces a wide range of physiological changes in the skin and its appendages, often overlooked in dermatologic practice. Catamenial dermatoses, influenced by hormonal fluctuations, present with cyclical …

Published: Sept. 25, 2025, midnight
68Ga-FAPI-04 PET/CT Demonstrates Subtype-specific Uptake Patterns in Endometriosis With Added Diagnostic Value Beyond MRI.

A 44-year-old woman with biopsy-proven endometriosis underwent 68Ga-FAPI-04 PET/CT. MRI revealed bilateral ovarian endometriomas, uterine adenomyosis, and deep pelvic endometriotic lesions. FAPI PET/CT demonstrated concordant uptake in deep infiltrating lesions …

Published: Sept. 24, 2025, midnight
The endocrine aspects of endometriosis.

Endometriosis is a chronic gynecologic disease of reproductive-age women, causing menstrual pain and infertility. Endocrine and inflammatory mechanisms drive its development, with estrogen/progesterone imbalance contributing to extrauterine implantation and persistence …

Published: Sept. 22, 2025, midnight
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