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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway.

Endometriosis‑associated infertility is considered to be linked to cellular senescence. The present study assessed whether rapamycin, a senescence inhibitor, ameliorates endometriosis‑associated infertility by upregulating peroxisome proliferator‑activated receptor α (PPARα) and …

Published: Oct. 31, 2025, midnight
Endometriosis During Adolescence: A Narrative Review.

Endometriosis in adolescents presents unique diagnostic and management challenges compared to its manifestation in adult women. The symptoms can vary significantly among individuals, often resulting in a substantial delay in …

Published: Oct. 31, 2025, midnight
MicroRNAs Regulating Oxidative Stress in Human Fertility: A Narrative Review of Mechanistic Insights and Clinical Potential.

Human infertility represents a multifaceted condition, with oxidative stress (OS) and microRNAs (miRNAs) emerging as key contributors to its pathophysiology. This comprehensive review explores the complex interplay between reactive oxygen …

Published: Oct. 31, 2025, midnight
Neuroendocrine-Immune Axis in Endometriosis: A Review on How the Nervous System Goes Beyond Pain Perception.

Endometriosis (EMS) is an estrogen-dependent disorder that affects about 10% of reproductive-age women. EMS affects female neuroendocrine and reproductive functions, greatly compromising female reproductive health and quality of life. However, …

Published: Oct. 31, 2025, midnight
Reproductive Outcomes After Laparoscopic Treatment of Endometriosis in Women with Infertility.

To assess the impact of laparoscopic treatment of endometriosis on pregnancy outcomes in women with infertility, performed either before or after failed fertility enhancement technology (FET). Secondary aims included evaluating …

Published: Oct. 31, 2025, midnight
Kissei Pharmaceutical’s Promising Phase III Study on Endometriosis Treatment - MSN

Kissei Pharmaceutical’s Promising Phase III Study on Endometriosis Treatment MSN

Published: Oct. 30, 2025, 11:45 a.m.
Hutchmed’s Promising Phase III Study on Advanced Endometrial Cancer Treatment - MSN

Hutchmed’s Promising Phase III Study on Advanced Endometrial Cancer Treatment MSN

Published: Oct. 30, 2025, 10:54 a.m.
Iovance Biotherapeutics Advances in Endometrial Cancer Treatment with Lifileucel Study - MSN

Iovance Biotherapeutics Advances in Endometrial Cancer Treatment with Lifileucel Study MSN

Published: Oct. 30, 2025, 10:49 a.m.
Integrative microbiome-metabolomics identifies Pseudomonas as a potential pathogenic factor in endometriosis.

Endometriosis (EMS) is a chronic disease characterized by unclear etiology, influenced by various genetic and environmental factors, with no definitive biomarkers available for early screening. Recent studies suggest that the …

Published: Oct. 30, 2025, midnight
Anti-Angiogenic RNAi-Based Treatment of Endometriosis in a Rat Model Using CXCR4-Targeted Peptide Nanoparticles.

Endometriosis is a common gynecological condition that affects fertility in many women of reproductive age worldwide. This multifaceted disease exhibits a pathogenesis characterized by hormonal and immune system dysregulations, alongside …

Published: Oct. 30, 2025, midnight
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