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Recent advancements and future applications of intrauterine drug delivery systems.

Intrauterine devices (IUDs) are drug-device combination products that are placed inside the uterus above the endometrium. IUDs contain a therapeutic agent used for contraception and have been shown to have …

Published: April 7, 2025, midnight
Gut microbiome in patients with early-stage and late-stage endometriosis.

Endometriosis is a chronic inflammatory gynecological disease. Previous studies have explored relationships between endometriosis and the microbiota, but none have focused on differences in gut microbiota between early-stage and late-stage …

Published: April 7, 2025, midnight
The role of gut and vaginal microbiomes in reproductive health: Implications for PCOS, endometriosis, pre-eclampsia, and beyond.

The interplay between the gut microbiome and reproductive health has gained increasing attention in recent years. Emerging research suggests that imbalances in the gut microbiome may impact reproductive function through …

Published: April 7, 2025, midnight
The impact of early diagnosis of endometriosis on quality of life.

Endometriosis is one of the most common chronic diseases in women, with a prevalence of up to 10%. The disease particularly affects women of reproductive age. Endometriosis has a significant …

Published: April 6, 2025, midnight
Identifying key palmitoylation-associated genes in endometriosis through genomic data analysis.

Palmitoylation, a post-translational lipid modification, has garnered increasing attention for its role in inflammatory processes and tumorigenesis. Emerging evidence suggests a potential association between palmitoylation and inflammatory responses in the …

Published: April 5, 2025, midnight
Role of miRNA polymorphisms on male and female infertility and recurrent implantation failure.

MiRNAs regulate gene expression, impacting reproductive health, such as infertility and implantation failure. This study investigated the association between miRNA polymorphisms and male infertility (azoospermia, oligospermia), female infertility (endometriosis), and …

Published: April 4, 2025, midnight
Womb for debate: the complexities of early-age hysterectomies.

Hysterectomy remains one of the most performed gynecologic procedures, yet its application in young and nulliparous individuals raises complex ethical, medical, and psychosocial considerations. As early detection of gynecologic conditions …

Published: April 4, 2025, midnight
Endometriosis MDC: role of the radiologist.

Endometriosis presents a common and significant health burden affecting approximately 1 in 10 reproductive age patients who are assigned female at birth. Recently guidelines have begun shifting away from laparoscopy …

Published: April 4, 2025, midnight
Bioinformatics analysis to identify environmental endocrine chemicals that target endometriosis genes.

Endometriosis (EMS) significantly impacts women's health and is influenced by genetic factors and environmental endocrine-disrupting chemicals (EDCs), which interfere with hormonal balance. Using the Gene Expression Omnibus database, we identified …

Published: April 4, 2025, midnight
Primary umbilical endometriosis in a nulliparous woman: A rare case report.

Endometriosis describes the presence of endometrial tissue outside the uterine cavity. These patients often experience cyclic pain, dysmenorrhea, dyspareunia and infertility. Extra-pelvic endometriosis, particularly at the umbilicus, is rare. The …

Published: April 4, 2025, midnight
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