TET3 is a common epigenetic immunomodulator of pathogenic macrophages.
Through a combination of single-cell/single-nucleus RNA-sequencing (sc/snRNA-seq) data analysis, immunohistochemistry, and primary macrophage studies, we have identified pathogenic macrophages characterized by TET3 overexpression (Toe-Macs) in three major human diseases associated …
The role of TGF-β superfamily in endometriosis: a systematic review.
Endometriosis is a prevalent chronic gynecological disorder. Globally, endometriosis affects approximately 5-10% of women of reproductive age, leading to symptoms such as dysmenorrhea, chronic pelvic pain, and infertility. While the …
Substitution of surgical care within benign gynaecology during COVID-19: waste of a good crisis? - a quantitative longitudinal study in the Netherlands.
To examine the impact of the COVID-19 pandemic on the substitution of surgical procedures in benign gynaecology in the Netherlands.