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Precision-based solutions for endometriosis: Integrating immunomics and drug repositioning strategies.

Endometriosis (EMs) is an estrogen-dependent, chronic inflammatory disorder characterized by immune microenvironment dysregulation, a critical factor in its pathogenesis. Despite existing therapies, limitations persist, highlighting the urgent need for innovative …

Published: Feb. 16, 2026, midnight
ESTROBOLOME: IS THERE A MISSING LINK?

Estrogens play an important role throughout a woman's life; therefore, disrupting their physiological production will alter hormonal balance with consequences for estrogen-related conditions, such as endometriosis and adenomyosis. The gut …

Published: Feb. 16, 2026, midnight
What Medicine Misses When It Refuses to Listen - The Good Men Project

What Medicine Misses When It Refuses to Listen The Good Men Project

Published: Feb. 15, 2026, 12:03 a.m.
Fertility after endometriosis surgery: a systematic review and meta-analysis comparison of primary versus multiple surgical interventions.

Symptoms of endometriosis are often incompletely managed and recurrent surgeries are commonplace. The impact of re-operation on fertility remains unclear. This systematic review compares fertility outcomes in patients who underwent …

Published: Feb. 15, 2026, midnight
Molecular mechanisms in endometriosis: linking JAK/STAT pathway, ferroptosis, and microbial dysbiosis.

Endometriosis is a chronic gynaecological disorder characterized by ectopic endometrial growth, inflammation, pain, and infertility. Current therapies, largely hormonal and surgical, have limited efficacy and compromise fertility, underscoring the need …

Published: Feb. 14, 2026, midnight
Retraction Note: APEX1/miR-24 axis: a promising therapeutic target in endometriosis.

Published: Feb. 13, 2026, midnight
Fragility Index Assessment of Randomised Trials Informing Endometriosis Management Guidance.

Published: Feb. 13, 2026, midnight
Misdiagnosis rate of endometriosis and strategies employed to identify endometriosis by analyzing patient characteristics in low-resource settings.

Endometriosis is a major gynecologic health issue affecting ~10% of women and girls of reproductive age worldwide. Despite its high prevalence, no curative treatment exists. Early diagnosis and treatment are …

Published: Feb. 13, 2026, midnight
2-Deoxyglucose dendrimer-enabled niclosamide delivery to FRβ-expressing macrophages alleviates endometriosis progression and associated hyperalgesia.

Endometriosis is a chronic, incurable disease. Due to limited efficacy, high recurrence rates, and serious side effects of current treatments, development of new, targeted, non-hormonal therapies is urgently needed. We …

Published: Feb. 12, 2026, midnight
Dietary Caloric Restriction Suppresses Endometriosis by Inhibiting STAT3/ERK Pathways.

Endometriosis is a chronic, estrogen-dependent inflammatory condition that affects approximately 10% of reproductive-age women and is frequently associated with infertility and pelvic pain. Unlike many estrogen-dependent disorders, epidemiologic studies have …

Published: Feb. 11, 2026, midnight
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