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Menstrual Effluent in the Pathogenesis and Diagnosis of Endometriosis-A Systematic Review.

Background: The individual and social burden of endometriosis is high, and the diagnosis is usually delayed by 7-10 years. Menstrual effluent (ME) represents an accessible and uniquely informative biofluid. This …

Published: Feb. 26, 2026, midnight
Association of endometriosis with hematuria markers: A Mendelian randomization study.

Identification of appropriate biomarkers is of great clinical significance for early diagnosis of endometriosis (EMs). This study aimed to comprehensively analyze the association between EMs and blood and urine biomarkers …

Published: Feb. 25, 2026, midnight
The problem with the 'truth': rethinking ground truth for artificial intelligence in endometriosis diagnosis.

Artificial intelligence (AI) is revolutionizing how we practice medicine. In areas where we have traditionally struggled, such as diagnosing endometriosis, AI has significant potential to improve the breadth and accuracy …

Published: Feb. 25, 2026, midnight
An Overview of Endometriosis and Potential Pharmacogenetic Targets.

Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial-like tissue outside the uterine cavity. It affects approximately 10-15% of women of reproductive age globally and is characterized …

Published: Feb. 25, 2026, midnight
Inverse association between cardiometabolic index and endometriosis in women of reproductive age: A cross-sectional, population-based study.

ObjectiveThis study aimed to investigate the relationship between the cardiometabolic index and the prevalence of endometriosis among reproductive-age women in the United States. This cross-sectional population-based study used data from …

Published: Feb. 25, 2026, midnight
Development of a novel meta-polygenic risk score for risk assessment and clinical manifestation prediction in systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease with multifactorial pathogenesis. Although polygenic risk scores (PRSs) have been developed to enable early prediction, their accuracy remains limited. To …

Published: Feb. 25, 2026, midnight
Endometriosis pain index: development of a model to predict poor pain-related quality of life after endometriosis surgery through machine learning analysis of registry data.

Predictive tools are lacking for pain-related outcomes after endometriosis surgery. The objective of this study was to develop and validate a machine learning-based clinical model to predict poor pain-related quality …

Published: Feb. 25, 2026, midnight
Ovarian Sclerosing Stromal Tumor. Spectrum of Ultrasound Findings. A Case Report and Review of Literature.

We present a case of a very rare benign ovarian tumor, a sclerosing stromal tumor (SST). In addition, we performed a review of the literature to describe the spectrum of …

Published: Feb. 25, 2026, midnight
Systems-level actions of luteolin in female reproductive disorders: from molecular mechanisms to clinical translation.

Female reproductive disorders represent a major global health challenge. Despite their clinical heterogeneity, these conditions share core pathological mechanisms including oxidative stress, chronic inflammation, hormonal imbalance, metabolic dysfunction, extracellular matrix …

Published: Feb. 25, 2026, midnight
Endometriosis-Related Impairment in Assisted Reproductive Technologies: Inflammatory Profiles, Oocyte Competence, and Embryo Development.

Background: Endometriosis is associated with infertility and impaired assisted reproductive technology (ART) outcomes, potentially due to an altered follicular microenvironment characterized by chronic inflammation. This study investigates the systemic and …

Published: Feb. 25, 2026, midnight
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