Endometriosis is a chronic gynecological pathology marked by the aberrant proliferation of tissue analogous to the endometrial lining outside the uterine cavity. This disorder frequently engenders persistent pelvic discomfort, infertility, …
Recent studies emphasize the role of immune dysregulation and inflammation in endometriosis (ES). While hormonal therapy remains the primary treatment, emerging research is exploring synergistic approaches that target inflammation. In …
This review explores the dual role of reactive oxygen species (ROS) and free radicals in the pathogenesis of endometriosis, aiming to deepen our understanding of these processes through a systematic …
Two-dimensional (2D) nanomaterials are of great interest due to their unique properties and broad biological applications. Among these, borophene, a single-atom-thick boron sheet with a honeycomb structure, exhibits exceptional structural, …
The adenosine monophosphate (AMP)-activated protein kinase (AMPK) signalling pathway regulates cell metabolism, inflammation and the immune response. This signalling pathway is essential for maintaining reproductive homeostasis and influencing steroidogenesis, implantation, …
Previous studies have shown that patients with a history of endometriosis have an increased susceptibility for developing a big number of comorbidities, including various autoimmune diseases. Endometriosis is a complex, …
Immunogenic Cell Death-Related Genes as Prognostic Biomarkers and Therapeutic Insights in Uterine Corpus Endometrial Carcinoma: An Integrative Bioinformatics Analysis Frontiers
Endometriosis is the extrauterine engraftment of endometrium-like tissue, causing chronic pain. Complex sensory-vascular-immune interactions, including growth factors, cytokines, and neuropeptides, are implicated in its pathophysiology, but the mechanisms remain unknown. …
Organon Halts Development of Endometriosis Drug OG-6219 After Mid-Stage Trial Failure geneonline.com
Immunological factors appear to play an important role in the development of endometriosis, as evidenced by the aberrant functioning of immune cells often observed in affected women. Although endometriosis is …