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Dual targeting of CXCR4 and EZH2 in endometriosis.

We recently showed that endometriotic peritoneal fluid (PF) altered the regulation of enhancer of zeste homolog 2 (EZH2) and H3K27me3. This study aimed to determine if PF by regulating EZH2/H3K27me3 …

Published: March 1, 2025, midnight
Smooth endoplasmic reticulum aggregates in human oocytes are related to female infertility etiology and diminished reproductive outcomes.

Smooth endoplasmic reticulum aggregates (SERa) are a type of dysmorphism in oocytes derived from controlled ovarian stimulation (COS). The effect of SERa on assisted reproductive techniques (ART) outcomes is debatable. …

Published: Feb. 28, 2025, midnight
Identification of FZD7 as a potential ferroptosis-related diagnostic gene in endometriosis by bioinformatics analysis.

An increasing number of research have suggested that ferroptosis plays an important role in endometriosis (EMS). This study was to identify a ferroptosis-related diagnosis gene in EMS by using bioinformatics. …

Published: Feb. 28, 2025, midnight
A systematic review and meta-analysis of advanced oxidative protein products levels (AOPP) levels in endometriosis: association with disease stage and clinical implications.

Endometriosis is a common cause of chronic pelvic pain and lacks precise pathophysiological mechanisms. Advanced oxidation protein products (AOPPs), markers of oxidative stress and inflammation, are implicated in pain-related diseases …

Published: Feb. 28, 2025, midnight
Endometriosis as a risk factor for ischemic and hemorrhagic stroke: a population-based cohort study.

We completed a retrospective population-based cohort study using administrative data from Ontario females from 1993-2015 to examine the association between a diagnosis of endometriosis and stroke. We identified 166 853 …

Published: Feb. 28, 2025, midnight
Case report of endometrioid carcinoma arising from the paraovarian cyst.

Paraovarian cysts develop near the ovaries and fallopian tubes in the pelvic region. We describe our experience with a case of endometrioid carcinoma arising from a paraovarian cyst to help …

Published: Feb. 28, 2025, midnight
Fertility preservation in women with endometriosis.

Endometriosis is a chronic disease that can compromise fertility in up to 30-50% of affected patients, and it is estimated that patients affected by endometriosis represent about 10% of patients …

Published: Feb. 28, 2025, midnight
Thoracic endometriosis syndrome diagnosed by dry thoracoscopy: Novel diagnostic method for a rare disease.

Endometriosis is an ectopic implantation of uterine tissue and can affect the thoracic cavity, resulting in Thoracic Endometriosis Syndrome (TES). TES is rare and presents with catamenial pneumothorax, haemothorax, and …

Published: Feb. 27, 2025, midnight
The Role of Adenogenesis Factors in the Pathogenesis of Endometriosis.

Endometriosis is a pathological condition characterized by the presence of the endometrial tissue, outside the uterine cavity. It affects nearly 10% of women of reproductive age and is responsible for …

Published: Feb. 27, 2025, midnight
Patterns of associations with epidemiologic factors by high grade serous ovarian cancer gene expression subtypes.

Ovarian high-grade serous carcinomas (HGSC) comprise four distinct molecular subtypes based on mRNA expression patterns, with differential survival. Understanding risk factor associations is important to elucidate the etiology of HGSC. …

Published: Feb. 26, 2025, midnight
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