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The Molecular and Cellular Mechanisms of Melatonin: From Physiological Actions to Clinical Applications in Reproductive Medicine.

Melatonin has evolved from its classical role as a pineal-derived circadian regulator to a molecule increasingly recognized for its mitochondrial and cytoprotective functions. This review examines the molecular mechanisms and …

Published: July 22, 2026, midnight
Integrating single-cell and bulk transcriptomic perturbation resources reveals complementary therapeutic spaces for drug repurposing.

Transcriptome-based drug repurposing can accelerate therapeutic discovery, but is limited by fragmented resources, inconsistent quality control, and reliance on single perturbation databases. We developed CDRPipe ( C omputational D rug …

Published: July 22, 2026, midnight
Profiling miRNA in salivary samples from subjects with endometriosis: a pilot study.

Endometriosis is a common, chronic, estrogen-dependent gynecological disorder characterized by the growth of endometrial-like tissue outside the uterus and frequently associated with pelvic pain and infertility. Despite its high prevalence, …

Published: July 22, 2026, midnight
Integrative serum proteomic and metabolomic profiling in ovarian endometrioma: an exploratory multi-omics study.

Ovarian endometrioma (OEM) is a common manifestation of endometriosis and is associated with both local lesions and systemic alterations. While immune dysregulation and metabolic disturbances have been individually reported in …

Published: July 22, 2026, midnight
Endometriosis: surgical management for fertility enhancement.

Endometriosis is a common, chronic inflammatory condition characterized by the presence of endometrium-like tissue outside of the uterus that can impact fertility through multiple mechanisms. In this review, the diagnosis, …

Published: July 22, 2026, midnight
Leven Rambin Nearly Died During ‘Routine’ Endometriosis Surgery: ‘All of This So I Can Prepare to Have Kids’ - SheKnows

Leven Rambin Nearly Died During ‘Routine’ Endometriosis Surgery: ‘All of This So I Can Prepare to Have Kids’ SheKnows

Published: July 21, 2026, 5:57 p.m.
‘Law & Order’ Star Odelya Halevi Says ‘Intense’ Pregnancy Mood Swings Are ‘Like Having a Split Personality’ - SheKnows

‘Law & Order’ Star Odelya Halevi Says ‘Intense’ Pregnancy Mood Swings Are ‘Like Having a Split Personality’ SheKnows

Published: July 21, 2026, 5:04 p.m.
p53-mediated epigenetic regulation in the pathogenesis of endometriosis.

Endometriosis (EMs) is a common gynecological disorder affecting reproductive‑aged women, characterized by ectopic endometrial growth and chronic pelvic pain that severely impairs quality of life. Although its pathogenesis remains incompletely …

Published: July 21, 2026, midnight
Menopause and Endometriosis - Symptoms and Risk of Malignant Transformation: A Systematic Review of the Literature.

To review the evidence concerning the clinical presentation of endometriosis in postmenopausal women and the associated risk of malignant transformation.

Published: July 21, 2026, midnight
Integrative Transcriptomic Analysis Identifies a Key Candidate Gene Bridging Inflammation and DNA Repair in Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by the ectopic implantation of endometrial-like tissue. Although retrograde menstruation is highly prevalent, only a subset of women develops the disease. This …

Published: July 21, 2026, midnight
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