This study investigateted the malignant transformation of endometriosis (EMS) into ovarian clear cell carcinoma (OCCC) using spatial transcriptomics and single-cell RNA sequencing (scRNA-seq) integration. Tissues with coexisting EMS and OCCC …
Pharmacogenetics is an emerging discipline that explores how genetic variants affect drug response, potentially leading to side effects or treatment failure. Although widely applied in other medical specialties, its use …
Endometriosis affects approximately 10% of reproductive-age women worldwide and is associated with substantial pain and mental health burden, yet its neurobiological correlates remain poorly characterized. Neuroimaging studies of endometriosis are …
Ovarian endometrioma (OMA) is the most prevalent form of endometriosis. Conservative surgical management of the condition is associated with a relatively high recurrence rate, the degree of which is potentially …
Low vitamin D levels have been associated with female infertility, but the underlying mechanisms are not understood.
Endometriosis is a chronic inflammatory disorder in which endometrial tissue grows outside the uterus, leading to pelvic pain and infertility. It remains a major challenge in women's health due to …
Infertility constitutes a major global health concern, affecting approximately 17.5% of couples of reproductive age. Although advances in assisted reproductive technologies (ART) have expanded treatment options, success rates remain highly …
Chronic pelvic pain affects one in four women. Botulinum toxin, approved for chronic migraine and cervical dystonia pain, is an emerging treatment for other pain conditions. We evaluated intramuscular pelvic …
Endometriosis affects approximately 10% of women of reproductive age and is associated with an increased risk of adverse pregnancy outcomes. However, the relationship between preeclampsia, endometriosis, and subsequent adverse pregnancy …
Background/Objectives: Endometriosis is a chronic inflammatory disease affecting up to 10-15% of women of reproductive age and is frequently associated with pelvic pain and infertility. Non-invasive biomarkers remain insufficient for …