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EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apoptotic form of …

Published: Dec. 19, 2025, midnight
APOL1-mediated kidney disease: a narrative review of the lessons learnt from the past 15 years.

Fifteen years have elapsed since the publication of the seminal work establishing the association between risk variants in the Apolipoprotein L1 (APOL1) gene and kidney disease in individuals of African …

Published: Dec. 17, 2025, midnight
Study Identifies FABP7 Protein as a Driver of Mobility and Stemness in Endometrial Cancer Cells - geneonline.com

Study Identifies FABP7 Protein as a Driver of Mobility and Stemness in Endometrial Cancer Cells geneonline.com

Published: Dec. 16, 2025, 10:35 p.m.
Towards understanding mare endometrosis: ex vivo study on the role of relaxin.

Mare endometrosis remains a poorly understood pathological process.

Published: Dec. 16, 2025, midnight
Delayed onset of HPV-associated uterine malignancies: seven pathogenetic factors in contrast to cervical cancer.

Human papillomavirus (HPV) is a well-established etiological agent for cervical cancer, yet its contribution to endometrial malignancies remains underrecognized and mechanistically distinct. This paper synthesizes current evidence to explain the …

Published: Dec. 13, 2025, midnight
Endometrial Protein Sparks Pre-Eclampsia and Development Issues - Bioengineer.org

Endometrial Protein Sparks Pre-Eclampsia and Development Issues Bioengineer.org

Published: Dec. 10, 2025, 11:22 a.m.
From Inflammation to Malignancy: The Link Between Endometriosis and Gynecological Cancers.

Endometriosis, a chronic estrogen-dependent disease, is associated with a risk of developing gynecological cancers. The mechanisms of this association remain unclear, but emerging evidence implicates key signaling pathways, including PI3K/AKT/mTOR …

Published: Dec. 7, 2025, midnight
Biochemical Heterogeneity of Endometriosis Phenotypes Revealed by FTIR Analysis.

Fourier-transform infrared (FTIR) spectroscopy was used to investigate molecular differences among peritoneal, ovarian, bowel endometriosis phenotypes and control tissues. Peritoneal lesions showed the most pronounced spectral changes in CH-stretching (2800-3000 …

Published: Nov. 30, 2025, midnight
Association between NHHR and endometriosis and the mediating role of the CALLY index: a cross-sectional study based on NHANES.

The ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR), a new lipid marker, can comprehensively reflect the lipid metabolic status of an individual. This study aimed to investigate …

Published: Nov. 28, 2025, midnight
Endometrial Stromal Cells from Endometriosis Patients Reflect Lesion-Type-Specific Heterogeneity.

Endometriosis, a disease affecting about one out of ten women, is characterized by the growth of endometrial-like tissue outside the uterine cavity. There is significant disease heterogeneity, but the pathophysiological …

Published: Nov. 28, 2025, midnight
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