Latest Articles

Delayed onset of HPV-associated uterine malignancies: seven pathogenetic factors in contrast to cervical cancer.

Human papillomavirus (HPV) is a well-established etiological agent for cervical cancer, yet its contribution to endometrial malignancies remains underrecognized and mechanistically distinct. This paper synthesizes current evidence to explain the …

[Immunology of fertilization, implantation and pregnancy: Key interactions and therapeutic perspectives].

The immunology of fertilization, implantation and pregnancy is based on a complex balance between maternal immune tolerance and a controlled inflammatory response. Adaptation of the maternal immune system is essential …

Laparoscopic Management of Cystic Adenomyosis Complicated with Deep Infiltrating Endometriosis.

Non-Invasive Methods for Early Diagnosis of Endometriosis-A Comprehensive Narrative Literature Review.

Endometriosis is a common gynecological pathology, with an incidence of nearly 10% in patients of reproductive age, and is still underdiagnosed. A thorough and well-spread diagnostic study of endometriosis based …

Role of Phytoestrogens in Endometriosis.

To investigate the therapeutic potential of phytoestrogens in the management of endometriosis and to elucidate their mechanisms of action based on current preclinical and clinical evidence.

ENDOMETRIOSIS IN WOMEN OF REPRODUCTIVE AGE IN KAZAKHSTAN: DIAGNOSTIC AND THERAPEUTIC DIFFICULTIES.

This review aims to examine the current diagnostic and therapeutic challenges associated with endometriosis in women of reproductive age in Kazakhstan and globally. The goal is to identify existing gaps …

Vaginal Contraception With NuvaRing Decreases Symptoms and Uterine Features of Adenomyosis: A Prospective Evaluation.

(Abstracted from Contraception 2025:150:111016, doi:10.1016/j.contraception.2025.111016) Adenomyosis occurs when ectopic endometrial glands invade the myometrium and can cause symptoms such as an enlarged uterus, heavy menstrual bleeding, pelvic pain, infertility, and …

Assessing the effectiveness of a pelvic pain management programme: does an endometriosis diagnosis influence outcome (a comparative analysis of outcomes in women with and without endometriosis).

Pain Management Programmes (PMPs) are recommended for chronic pain, but their effectiveness for endometriosis-associated chronic pelvic pain (CPP) remains unclear. This study evaluates outcomes from a specialised, multidisciplinary Pelvic Pain …

Burrowing behavior is a potential non-invasive proxy for lesion development in a syngeneic murine model of endometriosis.

Endometriosis (EM) is a persistent, chronic inflammatory condition associated with excruciating pelvic pain and infertility. The absence of a pre-clinical model that reliably replicates the clinical and functional hallmarks of …

Endometriosis: Pathophysiology and the Potential Role of Diet.

Endometriosis (ENDO) is a chronic, estrogen-dependent condition affecting over 190 million females worldwide. Characterized by cyclic pelvic pain, infertility, and systemic inflammation, its symptoms profoundly impact quality of life, interfering …