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PGRMC1 suppression enhances progesterone responsiveness in stromal cells of ovarian endometrioma.

Progesterone resistance in endometriosis reduces the efficacy of progestin. The non-classical progesterone receptor, progesterone receptor membrane component 1 (PGRMC1) may regulate progesterone signaling in the normal endometrium, but its expression …

Published: July 6, 2026, midnight
Catamenial pneumothorax complicated by massive right diaphragmatic hernia with solid organ herniation.

Catamenial pneumothorax is an uncommon manifestation of thoracic endometriosis syndrome, usually associated with small right-sided diaphragmatic fenestration. We report an extreme presentation in a woman in her late 40s who …

Published: July 6, 2026, midnight
The Association Between Endometriosis and an Increased Risk of Epithelial Ovarian Cancer and Cardiovascular Disease: Perspective on a Patient-Centered Approach to Endometriosis, a Heterogeneous Disease.

A growing body of literature has revealed that patients with endometriosis are at an increased risk for epithelial ovarian cancer (EOC) and cardiovascular disease (CVD). Endometriosis is a heterogeneous disease …

Published: July 6, 2026, midnight
Effect of Fish-Derived Lipids on Inflammation Status and Health-Related Quality of Life in Women with Endometriosis.

Background: Endometriosis is a chronic, estrogen-dependent inflammatory disorder associated with pain and immune dysregulation. Omega-3 (n-3) fatty acids and fish-derived bioactive lipids may modulate inflammation and metabolism. This study investigated …

Published: July 5, 2026, midnight
Steroidal alkaloids as multi-target therapeutics for the treatment of endometriosis.

Endometriosis is a chronic inflammatory disease characterised by ectopic endometrial tissue, progressive fibrosis and chronic pain, with a pathogenesis that goes beyond oestrogen dependence. The central question this review seeks …

Published: July 4, 2026, midnight
The Microbiome-Gut-Gonad Axis: How Microbial Metabolites Orchestrate Reproductive Physiology, Pathology, and Therapy.

The human microbiome, a dynamic endocrine organ, exerts profound systemic influence through the production of bioactive metabolites. While the microbiome-gut-brain axis is well-established, the direct conduit between the gut microbiota …

Published: July 4, 2026, midnight
Clear Cell Carcinoma of the Abdominal Wall: An Aggressive Endometriosis-Associated Malignant Disease.

Endometriosis rarely affects the abdominal wall and typically occurs following surgery, like uterine procedures or, more commonly, cesarean sections. There have been a few instances of endometriosis evolving into malignant …

Published: July 4, 2026, midnight
Bowel endometriosis: from pathogenesis to clinical management.

Bowel involvement is a severe manifestation of deep endometriosis that affects approximately 8-12% of women with endometriosis. Bowel endometriosis is most commonly localised in the rectosigmoid colon and frequently coexists …

Published: July 3, 2026, midnight
Guided immunotherapy for residual solid tumor: integrating platelets and CAR T cells to reduce post-surgical recurrence.

Postoperative recurrence remains a major obstacle to durable remission in patients with solid tumors, even after complete macroscopic resection. Growing evidence suggests that surgery creates a transient yet highly permissive …

Published: July 3, 2026, midnight
Low-FODMAP Diet for Gastrointestinal Symptoms in Endometriosis: A Systematic Review.

Background/Objectives: Gastrointestinal (GI) symptoms, including abdominal pain, bloating, altered stool pattern, dyschezia, and nausea, are frequent in women with endometriosis and may persist despite conventional gynecological treatment. The low fermentable …

Published: July 3, 2026, midnight
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