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Targeting inflammation in endometriosis: emerging therapeutic options.

Endometriosis is a chronic, estrogen-dependent inflammatory disease affecting up to 10% of reproductive-aged women. Current therapies are predominantly hormone-based and offer symptomatic relief without correcting the immune dysregulation and inflammation …

Published: Dec. 24, 2025, midnight
Global, Regional, and National Burden of Endometriosis, PCOS, and Unexplained Infertility and Their Attribution to Infertility, 1990-2021: Global Burden of Disease Study 2021.

Infertility is a growing global health issue affecting millions worldwide. While endometriosis, polycystic ovarian syndrome (PCOS) and unexplained infertility are recognized as the major contributors, their specific burden and impact …

Published: Dec. 23, 2025, midnight
Effectiveness of an anti-inflammatory diet before in vitro fertilisation in women with endometriosis: protocol for a randomised controlled trial.

Endometriosis is a common, benign, chronic inflammatory disease with multiple consequences, from chronic pain to systemic comorbidities and poor quality of life. As it usually affects people of reproductive age, …

Published: Dec. 23, 2025, midnight
MicroRNA Crossroads in PCOS and Endometriosis.

In the intricate landscape of health disorders in women, polycystic ovary syndrome and endometriosis stand out. Despite their complete etiology being unknown, their impact on women's health and link to …

Published: Dec. 23, 2025, midnight
Fertility preservation in endometriosis: current strategies and outcomes.

Endometriosis is a frequent chronic estrogen-dependent condition that can significantly impair fertility and reduce the quality of life in affected individuals. Women with endometriosis face a 30-50% risk of infertility. …

Published: Dec. 22, 2025, midnight
Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol-Driven WNT7B Suppression.

Adult endometrial glands undergo cyclic regeneration and development during the menstrual cycle. Their secretions are vital for endometrial functions and early pregnancy, yet the mechanisms controlling gland development are not …

Published: Dec. 22, 2025, midnight
Dysmenorrhoea presentation in Herlyn-Werner-Wunderlich syndrome: A case study.

Herlyn-Werner-Wunderlich syndrome is a rare congenital anomaly characterized by uterus didelphys, obstructed hemi-vagina, and ipsilateral renal agenesis. This study aims to present a case of Herlyn-Werner-Wunderlich syndrome seen at Shifa …

Published: Dec. 20, 2025, midnight
Correlation between Polycomb repressive complex proteins and epithelial-mesenchymal transition-associated genes in endometriotic tissues.

Endometriosis is a condition in which functional endometrial glands and stroma are found to grow outside the uterine cavity that can lead to symptoms like dysmenorrhea, dyspareunia, adhesions, and infertility. …

Published: Dec. 19, 2025, midnight
Usage of methods polarization-phase mueller-matrix introscopy for early diagnosis of endometriosis based on study of dehydrated films of peritoneal fluid.

Aim: To assess the effectiveness of early diagnosis of endometriosis using polarization-phase Muller-matrix introscopy methods of scattering dehydrated films of peritoneal fluid.

Published: Dec. 18, 2025, midnight
Could the estrobolome have a role in endometriosis pathogenesis and infertility? A systematic review.

Endometriosis is a chronic, estrogen-dependent condition affecting 10% of reproductive-aged women, often associated with infertility and chronic pelvic pain. Recent evidence suggests that gut microbiota dysbiosis and alterations in the …

Published: Dec. 18, 2025, midnight
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