Neutrophils initiate pro-inflammatory immune responses in early endometriosis lesion development.
Endometriosis is a chronic gynecological disease that affects 1 in 10 reproductive-aged women. Most studies investigate established disease; however, the initiation and early events in endometriotic lesion development remain poorly …
Single-cell and spatial transcriptomic profiling revealed niche interactions sustaining growth of endometriotic lesions.
Endometriosis is a chronic condition with limited therapeutic options. The molecular aberrations promoting ectopic attachment and interactions with the local microenvironment sustaining lesion growth have been unclear, prohibiting development of …