Trousseau's syndrome is a malignancy-associated hypercoagulable state characterized by recurrent or migratory thromboembolic events. Although frequently linked to adenocarcinomas, its association with endometrioid ovarian carcinoma in young patients is infrequently …
ProMetrioS is a randomized, blinded, placebo-controlled cross-over trial investigating the effect of a specific multispecies probiotic in patients with endometriosis. The aim of this clinical trial is to determine whether …
Endometriosis-associated ovarian cancer comprises a special group of ovarian cancers that most probably originate from endometriosis foci. Several in vitro studies have shown that microRNA (miRNA) plays an important role …
Inflammation is central to the pathogenesis of endometriosis. High-density lipoprotein (HDL)-related lipid ratios have been proposed as indicators of systemic metabolic inflammation, yet their associations with endometriosis status and ASRM …
The modified cardiometabolic index (MCMI), an integrated measure of visceral fat and lipid metabolism, has been widely applied in metabolic disease research. However, its relationship with endometriosis has not been …
To study whether incident endometriosis diagnosis, staging, and typology are associated with concurrent elevated serum inflammatory markers interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor alpha (TNF- α …
Adiposity influences reproductive function via endocrine and immune pathways. The association between body mass index (BMI) and anti-Müllerian hormone (AMH) in endometriosis is uncertain, and BMI may not fully capture …
Brenner tumors are rare ovarian neoplasms that often coexist with other epithelial tumors, most commonly mucinous cystic neoplasms. The association of Brenner tumors with endometriosis is unusual and not well-documented …
[This corrects the article DOI: 10.1371/journal.pone.0057724.].
Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form …