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Prevalence of Temporomandibular Disorders in Adult Women with Endometriosis.

Background/Objectives: The prevalence of endometriosis varies between 10% and 18%, while temporomandibular disorders (TMDs) concern between 29 and 34% of the general population. Both conditions share similar etiological factors and …

Published: Dec. 13, 2024, midnight
Thoracic Endometriosis Syndrome: A Comprehensive Review and Multidisciplinary Approach to Management.

Background: Endometriosis is a systemic, inflammatory, estrogen-dependent condition characterized by endometrial stroma and gland-like lesions outside of the uterus. It causes a range of symptoms, notably chronic pelvic pain, infertility …

Published: Dec. 13, 2024, midnight
Molecular-genetic characteristics of hmgb1 mrna expression in blood of women with endometriosis associated with infertility.

Aim: To examine HMGB1 expression in the blood of women with endometriosis-associated infertility and to establish its role in disease progression.

Published: Dec. 12, 2024, midnight
Missing and dismissing the impact of periods. Outcomes of focus groups of teens with period concerns.

Despite a high prevalence, menstrual issues are often normalised or trivialised and undermanaged in young people (YP). Uncontrolled dysmenorrhoea and heavy menstrual bleeding have a vastly negative impact on the …

Published: Dec. 12, 2024, midnight
N6-Methyladenosine Modification on the Function of Female Reproductive Development and Related Diseases.

N6-methyladenosine (m6A) modification is a widespread and reversible epigenetic alteration in eukaryotic mRNA, playing a pivotal role in various biological functions. Its significance in female reproductive development and associated diseases …

Published: Dec. 12, 2024, midnight
Utilizing AI for the Identification and Validation of Novel Therapeutic Targets and Repurposed Drugs for Endometriosis.

Endometriosis affects over 190 million women globally, and effective therapies are urgently needed to address the burden of endometriosis on women's health. Using an artificial intelligence (AI)-driven target discovery platform, …

Published: Dec. 12, 2024, midnight
Exploring Self-Reported Symptoms for Developing and Evaluating Digital Symptom Checkers for Polycystic Ovarian Syndrome, Endometriosis, and Uterine Fibroids: Exploratory Survey Study.

Reproductive health conditions such as polycystic ovary syndrome (PCOS), endometriosis, and uterine fibroids pose a significant burden to people who menstruate, health care systems, and economies. Despite clinical guidelines for …

Published: Dec. 12, 2024, midnight
Macranthoidin B restrains the epithelial-mesenchymal transition through COX-2/PGE2 pathway in endometriosis.

Macranthoidin B is one of the primary and unique triterpenoid saponin metabolites from Lonicera macranthoides Hand. -Mazz, which is used to treat endometriosis (EMS) in traditional Chinese medicine. However, the …

Published: Dec. 12, 2024, midnight
Endocrine disruptor chemicals exposure and female fertility declining: from pathophysiology to epigenetic risks.

Over the last decades, human infertility has become a major concern in public health, with severe societal and health consequences. Growing evidence shows that endocrine disruptors chemicals (EDCs) have been …

Published: Dec. 12, 2024, midnight
Management of Endometriosis-Related Pain: Comparing the Effectiveness of Hormonal Therapy, Surgical Interventions, and Complementary Therapies.

Endometriosis is a chronic, inflammatory disease characterized by the presence of endometrial-like tissue outside the uterus, affecting women of reproductive age. It is linked with debilitating pain, infertility, and a …

Published: Dec. 12, 2024, midnight
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