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Epidemiology of endometriosis based on real-world data in Japan.

Considering the progressively delayed age of pregnancy, what is the current epidemiology of endometriosis in Japan, including its prevalence, incidence and medication patterns, as revealed by a large-scale, real-world dataset?

Published: Nov. 2, 2025, midnight
MSN Labs Gets SEC Go-Ahead to Conduct Phase IV Clinical Trial on Elagolix for Endometriosis - Medical Dialogues

MSN Labs Gets SEC Go-Ahead to Conduct Phase IV Clinical Trial on Elagolix for Endometriosis Medical Dialogues

Published: Nov. 1, 2025, 11:55 a.m.
Effect of kisspeptin, neurokinin, and dynorphin neurons on regulation of reproduction.

Gonadotropin-releasing hormone pulsatility is under the influence of hypothalamic neuropeptides, especially neurons expressing kisspeptin, neurokinin B, and dynorphin. These hypothalamic cells are called KNDy neurons. By integrating hormonal and environmental …

Published: Nov. 1, 2025, midnight
Exosomes from miR-149-3p-transfected menstrual blood-derived mesenchymal stem cells ameliorate inflammation and migration of endometriosis cells.

Endometriosis carries remarkable social, public health, and financial consequences. Based on two theories of retrograde menstruation and stem cells, menstrual blood-derived stem cells (MenSCs) play a significant role in endometriosis …

Published: Nov. 1, 2025, midnight
Lactate-mediated immune suppression and MDSC expansion in endometriosis: Mechanisms and nanoparticle-targeted therapies.

Endometriosis, a chronic gynecological disorder characterized by the ectopic growth of endometrial-like tissue, is associated with severe pelvic pain, infertility, and profound immune dysregulation. Despite advances in hormonal therapy and …

Published: Nov. 1, 2025, midnight
Comparison of magnetic resonance imaging findings with and without intravenous contrast in women with pelvic endometriosis: A cross-sectional study.

Endometriosis is a common disease of the female genital system. Pelvic magnetic resonance imaging (MRI) is the best non-invasive diagnostic method for evaluating endometriosis.

Published: Nov. 1, 2025, midnight
FAK-dependent activation of src family kinase member BLK contributed to endometrial fibrosis via endoplasmic reticulum stress - Cell & Bioscience

FAK-dependent activation of src family kinase member BLK contributed to endometrial fibrosis via endoplasmic reticulum stress Cell & Bioscience

Published: Oct. 31, 2025, 9:23 a.m.
EVE Health Enters Commercial Rollout Phase for Dyspro and Libbo Following First Prescriptions and Purchase Orders - new.smallcaps.com.au

EVE Health Enters Commercial Rollout Phase for Dyspro and Libbo Following First Prescriptions and Purchase Orders new.smallcaps.com.au

Published: Oct. 31, 2025, 4:23 a.m.
Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway.

Endometriosis‑associated infertility is considered to be linked to cellular senescence. The present study assessed whether rapamycin, a senescence inhibitor, ameliorates endometriosis‑associated infertility by upregulating peroxisome proliferator‑activated receptor α (PPARα) and …

Published: Oct. 31, 2025, midnight
From Gut to Reproductive Health: Exploring Microbiome Interactions and Future Interventions.

Recent advances in microbiome research have illuminated the complex bidirectional interactions between gut health and reproductive well-being. Understanding the gut microbiome's influence on the reproductive system and vice versa reveals …

Published: Oct. 31, 2025, midnight
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