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Designing and validating a health promotion program for women with endometriosis: a mixed-methods study protocol.

Endometriosis is a benign and chronic gynecological estrogen-dependent disease. Research has shown that endometriosis can affect various dimensions of women's lives. It is recommended that programs be developed to improve …

Published: Aug. 26, 2025, midnight
3D map-guided modeling of functional endometrial tissue using multi-compartment assembloids.

The human endometrium is a dynamic tissue that lines the uterus and undergoes constant remodeling, making it especially susceptible to gynecological diseases like endometriosis and endometrial cancer. The molecular mechanisms …

Published: Aug. 23, 2025, midnight
A Cross-Sectional Study of Endometriosis Surgeries Across Obstetrics and Gynecology Subspecialties: Does Minimally Invasive Gynecologic Surgery (MIGS) Fellowship Training Make a Difference?

Objective The objective of this study was to compare the surgical approaches and postoperative outcomes of endometriosis surgeries performed by different obstetrics and gynecology (OBGYN) subspecialties: minimally invasive gynecologic surgery …

Published: Aug. 23, 2025, midnight
"It's like your body is fighting against you": a cross-sectional qualitative interview study of quality of life in U.S. Black women diagnosed with endometriosis.

Endometriosis is a chronic gynecological condition that significantly affects quality of life in an estimated 10-15% of women of reproductive age, yet Black women in the United States remain underrepresented …

Published: Aug. 21, 2025, midnight
Racial Disparities in Endometriosis and Pelvic Pain Treatment Within an Integrated Health Care Delivery System.

To assess disparities in medical and surgical management of endometriosis and pelvic pain disorders, focusing on Black individuals and individuals from other racial and ethnic groups within an integrated health …

Published: Aug. 21, 2025, midnight
Expression profiles of E-cadherin and N-cadherin in endometriosis and other gynecological diseases towards targeted treatment: a systematic review.

This systematic review aimed to summarize all available data and evaluate the roles of E-cadherin, N-cadherin, associated molecules, and signaling pathways in the pathogenesis of endometriosis. The search was conducted …

Published: Aug. 21, 2025, midnight
NR4A1 Acts as a Nutrient Sensor That Inhibits the Effects of Aging.

Orphan nuclear receptor 4A1 (NR4A1) is a member of the NR4A subfamily that was initially discovered as an intermediate early gene expressed in response to stressors, including inflammatory agents. This …

Published: Aug. 21, 2025, midnight
DRIVE-KG: Enhancing variant-phenotype association discovery in understudied complex diseases using heterogeneous knowledge graphs.

Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions, such as endometriosis which has been historically understudied despite …

Published: Aug. 21, 2025, midnight
The vaginal microbiome drives endometriosis pain.

Despite being one of two cardinal disease symptoms, endometriosis pain is poorly understood. Using a validated mouse model, we demonstrate that endometriosis-associated vaginal dysbiosis is sufficient to induce pain in …

Published: Aug. 21, 2025, midnight
Toward Sex-Specific Biomaterials Innovation: A Perspective.

Sex-related differences influence key biological processes relevant to biomaterials research, including tissue regeneration, immune response, drug metabolism, and relevant diseases. Despite increasing recognition of sex as a critical biological variable, …

Published: Aug. 20, 2025, midnight
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