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Challenges in conducting a feasibility randomized controlled trial of medicinal cannabis for endometriosis pain in Australia.

People with endometriosis report consuming cannabis to manage their endometriosis symptoms, however, its efficacy has not been established in clinical studies. This study aimed to determine the feasibility, acceptability, and …

Published: Sept. 23, 2025, midnight
Quality of Life Assessment and Clinical Implications for Women with Endometriosis Through Validated Tools: A Narrative Review.

Aim: The aim of the study was to synthesize validated patient-reported outcome measures (PROMs) for assessing health-related quality of life (HRQoL) in women with endometriosis and to outline their clinical …

Published: Sept. 23, 2025, midnight
The ExPAND Study: A Prospective Association Study into Endometriosis-Associated Pain, Neurosteroid Synthesis, and TRPM3.

Endometriosis-associated pain has debilitating effects on the quality of life of patients. Despite its high prevalence in reproductive-aged women, the pathophysiology is still unknown, impeding the development of targeted treatment …

Published: Sept. 23, 2025, midnight
The endocrine aspects of endometriosis.

Endometriosis is a chronic gynecologic disease of reproductive-age women, causing menstrual pain and infertility. Endocrine and inflammatory mechanisms drive its development, with estrogen/progesterone imbalance contributing to extrauterine implantation and persistence …

Published: Sept. 22, 2025, midnight
Unravelling the Intricate Link: Mast Cells and Estrogen-Induced Pain Sensitization in Endometriosis.

Endometriosis is a prevalent gynaecological disorder characterized by estrogen-dependent lesions. Pain-particularly dysmenorrhea, chronic pelvic pain, and dyspareunia-is the hallmark symptom of endometriosis. While pain mechanisms remain poorly understood, mast cells …

Published: Sept. 21, 2025, midnight
Clinical practice guidelines for the care of people experiencing chronic primary pain: protocol for a systematic review with interpretation against an established chronic pain care priority framework.

Most clinical practice guidelines (CPGs) for assessing and managing people's chronic pain focus on specific pain conditions, body sites or life course stages. This creates complexity for clinicians making care …

Published: Sept. 18, 2025, midnight
Exploring Oxidative Stress in Different Endometriosis Phenoptypes: Insights from Ovarian and Systemic Perspectives by the Study of SIRT3.

Endometriosis affects about 10% of reproductive-aged women, characterized by endometrial-like tissue outside the uterus, leading to chronic inflammation. The exact cause remains unknown, though genetic and epigenetic factors are increasingly …

Published: Sept. 18, 2025, midnight
Tolerability and Shared Decision-Making in the Hormonal Management of Endometriosis-Associated Pain.

Background: The management of endometriosis-associated pain has traditionally focused on analgesic efficacy. However, with high-level evidence demonstrating therapeutic equivalence among principal hormonal classes, the paradigm has shifted towards a patient-centred …

Published: Sept. 18, 2025, midnight
Insights from focus groups with trans and gender-diverse people with endometriosis: stories you tell, stories you don't.

Endometriosis is a chronic condition characterised by cyclic pain symptoms that often significantly affect health-related quality of life. Predominantly framed as a "woman's condition," current research overlooks the experiences of …

Published: Sept. 17, 2025, midnight
The effects of music listening intervention on postoperative care in unilateral vs. bilateral endometriotic cysts.

Endometriosis is a chronic gynecological condition that can result in pelvic pain and infertility, thereby significantly impacting women's reproductive health. Psychological disorders such as anxiety and depression are common in …

Published: Sept. 15, 2025, midnight
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